41192-80-7 Usage
Uses
Used in Pharmaceutical Research:
2-Trifluoromethylquinolin-8-ol is utilized as a building block in chemical synthesis for the development of new pharmaceuticals. Its unique structure and properties allow for the creation of novel compounds with potential therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-Trifluoromethylquinolin-8-ol is employed as a key intermediate in the synthesis of various bioactive molecules. Its trifluoromethyl group can enhance the compound's lipophilicity, metabolic stability, and overall drug-like properties, which are crucial for the design of effective drugs.
Used in Drug Development:
2-Trifluoromethylquinolin-8-ol plays a significant role in drug development, where its trifluoromethyl group can modulate the biological activity of the compound. This modification can lead to improved pharmacokinetics, such as better absorption, distribution, metabolism, and excretion profiles, ultimately contributing to the development of more effective and safer drugs.
Used in Chemical Synthesis:
As a chemical compound with unique solubility properties, 2-Trifluoromethylquinolin-8-ol is used in various chemical synthesis processes. Its ability to dissolve in different solvents can facilitate reactions and improve the overall yield of the synthesized products.
Check Digit Verification of cas no
The CAS Registry Mumber 41192-80-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,1,9 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41192-80:
(7*4)+(6*1)+(5*1)+(4*9)+(3*2)+(2*8)+(1*0)=97
97 % 10 = 7
So 41192-80-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H6F3NO/c11-10(12,13)8-5-4-6-2-1-3-7(15)9(6)14-8/h1-5,15H
41192-80-7Relevant academic research and scientific papers
New regiospecific synthesis of 2-trifluoromethyl-1,5 diazapentadiene compounds and of 2-trifluoromethylquinolines, their cyclization products
El Kharrat, Salem,Skander, Myriem,Dahmani, Abdelkader,Laurent, Philippe,Blancou, Hubert
, p. 8327 - 8331 (2007/10/03)
2-Trifluoromethylquinolines 5 are synthesized in high yields using a perfluoroalkylated gemiodoacetoxy derivative 3 and arylamines 4. The intermediate of this reaction, 2-trifluoromethyl-1,5-diazapentadiene compound 6, was isolated. The procedures are eas
A novel synthesis of 2-fluoroalkyl quinolines
Wang, Quan-Fu,Mao, Yun-Yu,Qin, Chao-Yue,Zhu, Shi-Zheng,Hu, Chang-Ming
, p. 55 - 63 (2007/10/03)
2-Fluoroalkyl quinolines are prepared by reacting aniline with α-fluoroalkyl aldehydes or α-fluoroalkyl cyclohexanones in the presence of acetic acid. Under the same reaction condition, 2-aminophenol gives the corresponding 2-fluoroalkyl-8-quinolinols; in some cases, 2-fluoroalkyl benzoxazoles are also formed as minor products.
