41198-89-4

Basic information

• Product Name: 1-Cyclohexene-1-carbonitrile, 4-methyl-
• CAS NO: 41198-89-4
• Molecular Formula: C8H11N
• Molecular Weight: 121.182
• Mol File: 41198-89-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-Cyclohexene-1-carbonitrile, 4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Cyclohexene-1-carbonitrile, 4-methyl-(41198-89-4)
• EPA Substance Registry System: 1-Cyclohexene-1-carbonitrile, 4-methyl-(41198-89-4)

Safety Data

• Hazardous Substances Data: 41198-89-4(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Odor

Slightly fruity

Applications

a. Intermediate in the synthesis of pharmaceuticals
b. Intermediate in the synthesis of agrochemicals
c. Intermediate in the synthesis of other organic compounds
d. Solvent
e. Production of dyes and pigments

Functional groups

a. Cyclohexene
b. Carbonitrile

Toxicity

Low toxicity

Safety

Generally regarded as safe for use in various industrial processes

Upstream product

• 589-92-4 1-methylcyclohexan-4-one 
• 97540-74-4 4-Methyl-cyclohex-1-enecarbaldehyde oxime 
• 31053-83-5 4-methyl-1-cyclohexenyl chloride 
• 151-50-8 potassium cyanide 
• 933-45-9 1-hydroxy-4-methyl-cyclohexanecarbonitrile 

Downstream Products

• 34147-56-3 4-methyl-1-cyclohexanemethylamine 
• 75233-43-1 1-Cyano-1-(4-hydroxy-3-nitro-2-butyl)-4-methyl-2-cyclohexene 
• 75233-42-0 4-Methyl-1-[1-methyl-2-nitro-3-(tetrahydro-pyran-2-yloxy)-propyl]-cyclohex-2-enecarbonitrile 
• 100860-12-6 4-methyl-cyclohex-1-enecarboxylic acid amide 

Relevant articles and documents

CYCLOALKYLNITRILE PYRAZOLE CARBOXAMIDES AS JANUS KINASE INHIBITORS

Cycloalkylnitrile pyrazole carboxamides as JAK inhibitors useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer are provided.

Cyanation of 1-Halocycloalkenes Catalyzed by Tetracyanocobaltate(I). Convenient Synthesis of 1-Cyanocycloalkenes

1-Cyanocycloalkenes (1-cyanocyclopentene, -hexene, -heptene, and -octene) were readily synthesized by catalytic cyanation of the corresponding 1-halocycloalkenes with tetracyanocobaltate(I).Reactivities of methyl-substituted 1-chlorocyclohexenes were lower than that of 1-chlorocyclohexene, and 1-chloro-2-methylcyclohexene scarecely reacted.Hydrogenation and isomerization of 1-cyanocycloalkenes were observed only with 1-cyanocycloheptene and 1-cyano-6-methylcyclohexene, respectively.