34147-56-3

Usage

Uses

Used in Chemical Manufacturing:
4-Methyl-cyclohexaneMethanaMine is utilized as a key intermediate in the production of a wide range of chemical compounds, contributing to the synthesis of diverse products.
Used as a Solvent:
4-Methyl-cyclohexaneMethanaMine also functions as a solvent in various industrial applications, facilitating processes that require the dissolution of specific substances.
Used in Pharmaceutical Production:
4-Methyl-cyclohexaneMethanaMine is employed as an intermediate in the manufacturing of pharmaceuticals, playing a crucial role in the development of medications.
Used in Pesticide Production:
In the agricultural sector, 4-Methyl-cyclohexaneMethanaMine is used in the production of pesticides, helping to create effective solutions for pest control.
Safety Measures:
Due to potential hazards associated with inhalation, ingestion, and skin contact, it is essential to implement proper safety measures when handling 4-Methyl-cyclohexaneMethanaMine.

Upstream product

• 589-92-4 1-methylcyclohexan-4-one 
• 500546-09-8 4-methylcyclohexane-1-carboxamide 
• 524048-18-8 4-methylcyclohexane-1-carbonitrile 
• 99-94-5 p-Toluic acid 
• 71-41-0 pentan-1-ol 
• 41198-89-4 4-methylcyclohex-1-ene-1-carbonitrile 
• 64-17-5 ethanol 
• 98552-84-2 (Ξ)-4-Methyl-1-nitromethyl-cyclohexanol 

Downstream Products

• 1622159-79-8 trans-2-fluoro-N-[(4-methylcyclohexyl)methyl]pyridine-4-carboxamide 
• 1622159-80-1 cis-2-fluoro-N-[(4-methylcyclohexyl)methyl]pyridine-4-carboxamide 

Relevant academic research and scientific papers

One-pot reductive amination of carboxylic acids: a sustainable method for primary amine synthesis

The reductive amination of carboxylic acids is a very green, efficient and sustainable method for the production of (bio-based) amines. However, with current technology, this reaction requires two to three reaction steps. Here, we report the first (heterogeneous) catalytic system for the one-pot reductive amination of carboxylic acids to amines, with solely H2 and NH3 as the reactants. This reaction can be performed with relatively cheap ruthenium-tungsten bimetallic catalysts in the green and benign solvent cyclopentyl methyl ether (CPME). Selectivities of up to 99% for the primary amine could be achieved at high conversions. Additionally, the catalyst is recyclable and tolerant for common impurities such as water and cations (e.g. sodium carboxylate).

Corresponding amine nitrile and method of manufacturing thereof

The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.

Preparation of primary amines

Primary aliphatic amines are prepared by reacting a corresponding aliphatic oxime with hydrazine in the presence of Raney nickel.