41201-60-9

Basic information

• Product Name: SULINDAC INTERMEDIATE
• Synonyms: SULINDAC INTERMEDIATE;6-FLUORO-2-METHYL-3-(P-METHYLTHIOBENZYL)-1H-INDENE;5-FLUORO-2-METHYL-1-(4-METHYLSULFANYL-BENZYL)-1H-INDENE;6-FLUORO-2-METHYL-3-(4-METHYLSULFANYL-BENZYL)-1H-INDENE;6-Fluoro-2-Methyl-3-(4-Methylthiobenzyl)-1H-indene;5-Fluoro-2-Methyl-1-(p-Methylthiobenzyl)- Indene;5-Fluoro-2-Methyl-1-(4-Methylthiobenzyl)indene;6-Fluoro-2-methyl-3-[[4-(methylthio)phenyl]methyl]-1H-indene
• CAS NO: 41201-60-9
• Molecular Formula: C₁₈H₁₇FS
• Molecular Weight: 284.3909832
• EINECS: 405-410-7
• Mol File: 41201-60-9.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 411.8°C at 760 mmHg
• Flash Point: 202.8°C
• Appearance: /
• Density: 1.18g/cm³
• Vapor Pressure: 1.3E-06mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: SULINDAC INTERMEDIATE(CAS DataBase Reference)
• NIST Chemistry Reference: SULINDAC INTERMEDIATE(41201-60-9)
• EPA Substance Registry System: SULINDAC INTERMEDIATE(41201-60-9)

Safety Data

• Hazardous Substances Data: 41201-60-9(Hazardous Substances Data)

Usage

General Description

Sulindac Intermediate is a chemical compound primarily used in the production of Sulindac, a non-steroidal anti-inflammatory drug (NSAID) commonly utilized for treating various conditions like arthritis, acute gout, and bursitis. As an imperative component in the synthesis of this medical drug, Sulindac Intermediate plays a crucial role in the pharmaceutical industry. The specific properties and effects of Sulindac Intermediate depend on its subsequent processing and the other compounds it is combined with during the creation of Sulindac.

InChI:InChI=1/C18H17FS/c1-12-9-14-11-15(19)5-8-17(14)18(12)10-13-3-6-16(20-2)7-4-13/h3-8,11H,9-10H2,1-2H3

Upstream product

• 874-87-3 1-(chloromethyl)-4-methylthiobenzene 
• 41201-58-5 5-Fluoro-2-Methyl-Indan-1-One 

Downstream Products

• 38194-50-2 Sulindac 
• 41201-62-1 (+/-)-6-Fluoro-3-(4-methanesulfinylbenzyl)-2-methyl-1H-indene 

Relevant articles and documents

Esters and amides of substituted indenyl acetic acids

Esters and amides of substituted indenyl acetic acids of the formula: n is an integer of at least 2;, Q is a deprotonated residue of polymer or macromolecular structure having a molecular weight of at least about 1000 containing at least two primary and/or secondary amino groups and/or hydroxy groups;, R1 is selected from hydrogen, lower alkyl, or haloalkyl;, R2 is selected from hydrogen or alkyl;, R3 and R4 are one or more members each independently chosen from hydrogen, alkyl, acyloxy, alkoxy, nitro, amino, acylamino, alkylamino, diakylamino, dialkylaminoalkyl, sulfamyl, alkythio, mercapto, hydroxy, hydroxyalkyl, alkylsulfonyl, halogen, cyano, carboxyl, carbalkoxy, carbamido, haloalkyl or cycloalkoxy; and, R5 is selected from alkylsulfenyl, alkylsulfinyl or alkylsulfonyl. are useful in the treatment of colonic polyps.