412026-78-9

Basic information

• Product Name: N-benzyl-N-(2-oxoethyl)acetamide
• Synonyms: N-benzyl-N-(2-oxoethyl)acetamide
• CAS NO: 412026-78-9
• Molecular Weight: 191.23
• Mol File: 412026-78-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(2-oxoethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(2-oxoethyl)acetamide(412026-78-9)
• EPA Substance Registry System: N-benzyl-N-(2-oxoethyl)acetamide(412026-78-9)

Safety Data

• Hazardous Substances Data: 412026-78-9(Hazardous Substances Data)

Upstream product

• 18793-07-2 3-benzylidenamino-propane-1,2-diol 
• 100-52-7 benzaldehyde 
• 784208-81-7 1,2-diacetoxy-3-(acetyl-benzyl-amino)-propane 
• 54127-58-1 3-benzylamino-1,2-dihydroxypropane 
• 104-63-2 N-Benzylethanolamine 
• 412027-01-1 N-benzyl-N-(2,3-dihydroxy-propyl)-acetamide 

Downstream Products

• 79179-76-3 1-acetyl-4-benzyl-3-oxopiperazine 

Relevant articles and documents

α-Amidoaldehydes as Substrates in Rhodium-Catalyzed Intermolecular Alkyne Hydroacylation: The Synthesis of α-Amidoketones

We show that readily available α-amidoaldehydes are effective substrates for intermolecular Rh-catalyzed alkyne hydroacylation reactions. The catalyst [Rh(dppe)(C6H5F)][BArF4] provides good reactivity, and allows a broad range of aldehydes and alkynes to be used as substrates, delivering α-amidoketone products. High yields and high levels of regioselectivity are achieved. The use of α-amidoaldehydes as substrates establishes that 1,4-dicarbonyl motifs can be used as controlling groups in Rh-catalyzed hydroacylation reactions.