412048-26-1

Basic information

• Product Name: dimethyl 2-methyl-2-phenylcyclopropane-1,1-dicarboxylate
• Synonyms: dimethyl 2-methyl-2-phenylcyclopropane-1,1-dicarboxylate
• CAS NO: 412048-26-1
• Molecular Weight: 248.279
• Mol File: 412048-26-1.mol

Chemical Properties

• CAS DataBase Reference: dimethyl 2-methyl-2-phenylcyclopropane-1,1-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-methyl-2-phenylcyclopropane-1,1-dicarboxylate(412048-26-1)
• EPA Substance Registry System: dimethyl 2-methyl-2-phenylcyclopropane-1,1-dicarboxylate(412048-26-1)

Safety Data

• Hazardous Substances Data: 412048-26-1(Hazardous Substances Data)

Upstream product

• 98-83-9 isopropenylbenzene 
• 868-26-8 dimethyl 2-bromomalonate 
• 6773-29-1 dimethyl diazomalonate 
• 1379474-24-4 dimethyl 2-((2-methoxyphenyl)-λ³-iodanylidene)malonate 
• 145838-86-4 bis(methoxycarbonyl)(phenyliodinio)methanide 

Downstream Products

• 1402823-98-6 (E)-dimethyl 1-isopropyl-2-(isopropylimino)-5-methyl-5-phenylpyrrolidine-3,3-dicarboxylate 
• 1519050-45-3 dimethyl 5-methyl-2,5-diphenyl-4,5-dihydro-3H-pyrrole-3,3-dicarboxylate 
• 1577201-92-3 dimethyl 2-((N,4-dimethylphenyl)sulfonamido)-4-methyl-3-pentyl-4-phenylcyclopent-2-ene-1,1-dicarboxylate 

Relevant articles and documents

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Iodonium ylide 2, derived front dimethyl malonate, undergoes facile thermal cycloaddition with alkenes and dienes catalyzed with Rh2(OAc)4 to form the corresponding cyclopropanedicarboxylates and vinylcyclopropanedicarboxylates, resp

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Isocyanates, isothiocyanates, and carbodiimides are effective substrates in (3 + 2) cycloadditions with donor-acceptor cyclopropanes for the synthesis of five-membered heterocycles. These reactions exhibit a broad substrate scope, high yields, and well-defined chemoselectivity. Discussed herein are the implications of Lewis acid choice on the stereochemical outcome and the reaction mechanism.

Lewis acid mediated (3 + 2) cycloadditions of donor-acceptor cyclopropanes with heterocumulenes

Isocyanates, isothiocyanates, and carbodiimides are effective substrates in (3 + 2) cycloadditions with donor-acceptor cyclopropanes for the synthesis of five-membered heterocycles. These reactions exhibit a broad substrate scope, high yields, and well-defined chemoselectivity. Discussed herein are the implications of Lewis acid choice on the stereochemical outcome and the reaction mechanism.

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