412050-51-2

Upstream product

• 403796-40-7 (Z)-N¹-(2-fluorobenzyl)-N²-(2-amino-1,2-dicyanovinyl)formamidine 
• 89-99-6 2-fluorobenzylamine 
• 154909-85-0 5-amino-N¹-(2-fluorobenzyl)-4-cyanoimidazole 

Downstream Products

• 412050-53-4 5-amino-N¹-(2-fluorobenzyl)-3H-imidazo[4,5-b]pyridine-6-carbonitrile 

Relevant academic research and scientific papers

Synthesis of 1-substituted 5-aminoimidazole-4-carbaldehydes and 8-amino-1-(2-fluorobenzyl)imidazo[4′,5′:5,6]pyrido[2,3-d] pyrimidine

The syntheses of a number of 1-substituted 5-aminoimidazole-4-carbaldehydes 3, by the reduction of the corresponding 5-amino-4-cyanoimidazole derivatives is reported using LiAlH(OEt)3, prepared in situ from LiAlH4 and ethyl acetate. The compounds of type 1 are useful intermediates for the synthesis of elongated adenine derivatives.