412331-97-6Relevant academic research and scientific papers
Automated commercial synthesis system for preparation of O-(2-[18F]fluoroethyl)-L-tyrosine by direct nucleophilic displacement on a resin column
Tang, Ganghua,Tang, Xiaolan,Wang, Mingfang,Luo, Lei,Gan, Manquan,Huang, Zuhan
, p. 645 - 660 (2007/10/03)
A slightly modified automated commercial synthesis system for preparation of O-(2-[18F]fluoroethyl)-L-tyrosine (FET), an amino acid tracer for tumor imaging with positron emission tomography, is described. Direct nucleophilic fluorination of [18F]fluoride
Synthesis and evaluation of a novel series of farnesyl protein transferase inhibitors as non-peptidic CAAX tetrapeptide analogues
Perez, Michel,Maraval, Catherine,Dumond, Stephan,Lamothe, Marie,Schambel, Philippe,Etievant, Chantal,Hill, Bridget
, p. 1455 - 1458 (2007/10/03)
A novel series of compounds, derived from 4-amino-phenyl piperazine, has been designed to selectively inhibit farnesyl protein transferase (FPTase) as CAAX tetrapeptide analogues. Certain of these compounds were shown to possess low nanomolar inhibitory a
