4125-79-5 Usage
Uses
Used in Organic Chemistry:
H-Arg(Z)2-OH is used as a building block for the synthesis of peptides and proteins, facilitating the selective reactions with other functional groups due to the protective Z group.
Used in Solid-Phase Peptide Synthesis:
H-Arg(Z)2-OH is utilized as a key component in solid-phase synthesis, allowing for the stepwise assembly of peptide chains in a controlled and efficient manner.
Used in Pharmaceutical Development:
H-Arg(Z)2-OH is employed as a reagent in the preparation of peptide-based drugs, contributing to the development of novel pharmaceuticals with potential therapeutic applications.
Used in Peptide Chemistry Research:
H-Arg(Z)2-OH is applied in research to explore the properties and reactions of peptides, furthering the understanding of peptide chemistry and its applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 4125-79-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,2 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4125-79:
(6*4)+(5*1)+(4*2)+(3*5)+(2*7)+(1*9)=75
75 % 10 = 5
So 4125-79-5 is a valid CAS Registry Number.
4125-79-5Relevant academic research and scientific papers
Total synthesis of cyclotheonamide C by use of an α-keto cyanophosphorane methodology for peptide assembly
Roche, Stephane P.,Faure, Sophie,El Blidi, Lahssen,Aitken, David J.
experimental part, p. 5067 - 5078 (2009/05/07)
The total synthesis of cyclotheonamide C (3), a macrocyclic pentapeptide incorporating an α-keto homoarginine (k-Arg) and a vinylogous dehydrotyrosine (V-ΔTyr) unit, has been achieved. For comparison of macrocyclisation feasibility, two linear pentapeptides bearing free ketone functions at the k-Arg units were prepared, by use of tandem oxidation/coupling reactions on α-keto cyanophosphorane precursors as the key processes for pentapeptide elaboration. Successful activation and coupling at the pentapeptide V-ΔTyr C terminus led to the target molecule core, and thus provided a short total synthesis of the target compound. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
