41255-02-1Relevant academic research and scientific papers
A facile, general synthesis of 3,4-difluoro-6-substituted-2-pyrones
Wang, Yi,Burton, Donald J.
, p. 3859 - 3862 (2007/10/03)
Reaction of (2E)-2,3-difluoro-3-iodoacrylic acid with a variety of terminal acetylenes under cocatalysis of PdCl2(PPh3)2 and Cul gave difluorinated 2-pyrones as the sole product in good yields.
Fluorinated Pyrones and Cyclobutenecarboxylates
England, David C.,Donald, Elaine A.,Weigert, Frank J.
, p. 144 - 147 (2007/10/02)
Fluorinated α-pyrones 6 have been prepared from perfluoroacryloyl fluorides 1 and 2 by reaction with arylacetylenes and/or methyl ketones.Cyclobutenecarboxylates 8 have also been obtained from the reactions of 1 with acetylenes.The NMR spectrum of pyrone 6e shows unusually long-range fluorine-fluorine coupling.
