41270-89-7

Basic information

• Product Name: N,N-dimethyl-2,6-diphenylpyrimidin-4-amine
• Synonyms: N,N-dimethyl-2,6-diphenylpyrimidin-4-amine
• CAS NO: 41270-89-7
• Molecular Weight: 275.353
• Mol File: 41270-89-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-2,6-diphenylpyrimidin-4-amine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-2,6-diphenylpyrimidin-4-amine(41270-89-7)
• EPA Substance Registry System: N,N-dimethyl-2,6-diphenylpyrimidin-4-amine(41270-89-7)

Safety Data

• Hazardous Substances Data: 41270-89-7(Hazardous Substances Data)

Upstream product

• 127-19-5 N,N-dimethyl acetamide 
• 100-47-0 benzonitrile 
• 58979-04-7 C₁₈H₂₀N₂ 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 19176-75-1 3,3,3-tris(dimethylamino)-1-phenyl-prop-2-yne 
• 1670-14-0 benzamidine monohydrochloride 

Relevant articles and documents

2-Aza-1,3-dienes with electron-releasing substituents at the 1,3 positions. Reagents for the construction of pyridine and pyrimidine derivatives

New 2-aza-1,3-dienes bearing 1 and 3-donor substituents are prepared from N-thioacylacetamidines through deprotonation of N-ylidene acetamidinium iodides. The 2-aza-3-(dimethylamino)-1-(methylthio)-1-phenylbutadiene (3) is trapped in situ by the residual precursor salt acting as a heterodienophile to give the pyrimidine 5. Substituted 2-aza-1-(dimethylamino)-3-(methylthio) analogues react readily with a variety of electron-deficient dienophiles to yield pyridine or pyrimidine derivatives. The stereochemistry of the hetero Diels-Alder reaction in the cases of dimethyl fumarate and acrylonitrile has been assigned by X-ray diffraction analyses of the resulting tetrahydropyridines and corresponds to an exo selectivity. The number and nature of cycloadducts in the cases of dimethyl acetylenedicarboxylate and phenyl isothiocyanate depend on C-4 substitution. The results obtained from the C-4 unsubstituted azabutadiene 8 are explained by an allylic rearrangement involving the 1,3-migration of dimethylamino group in the primary [4+2] adduct.

Synthesis of tri-or tetrasubstituted pyrimidine derivatives through the [5+1] annulation of enamidines with either N,N-dimethylformamide dialkyl acetals or orthoesters and their application in a ring transformation of pyrimidines to pyrido[2,3-d]pyrimidin

The [5+1] annulation of enamidines, which were prepared from functionalized silanes, organolithium compounds and two nitriles, with N,N-dimethylformamide dialkyl acetals as the C1 unit is described, leading to the synthesis of tri- and tetrasubstituted py