41301-27-3Relevant academic research and scientific papers
A modified synthesis of (Z)-pyrethrolone
Markham, Todd E.,Duggan, Peter J.,Johnston, Martin R.
, p. 99 - 109 (2022/03/16)
An accessible, efficient, and reliable synthesis for the production of (Z)-pyrethrolone remains necessary as previous syntheses suffer from drawbacks including the use of toxic reagents, expensive starting materials and lack of regioselectivity in the production of key intermediates. This work attempts to alleviate the issues of prior syntheses by making use of well-known and regioselective transformations for the efficient synthesis of (Z)-pyrethrolone. Ultimately, (Z)-pyrethrolone is generated in an overall 20% yield over five steps from a cheap, easily accessible starting material using reliable, optimised transformations.
Process for producing cyclopropanecarboxylates
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, (2008/06/13)
There is disclosed a process process for producing a cyclopropanecarboxylate of formula (1): 1which process comprises reacting cyclopropanecarboxylic acid of formula (2): 2with a monohydroxy compound of formula (3): R6OH??(3),in the presence of a catalyst compound comprising an element of to Group 4 of the Periodic Table of Elements.
Process for preparing 4-hydroxy-2-cyclopentenones
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, (2008/06/13)
A process for producing a compound of the formula: STR1 wherein R1 is a hydrogen atom, an alkyl group or an alkenyl group and R2 is an alkyl group, an alkenyl group or an alkynyl group, which comprises treating a compound of the formula: STR2 wherein R1 and R2 are each as defined above and R is a hydrogen atom or a lower alkyl group in the presence of an acidic substance and water.
Process for producing 4-cyclopentenones
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, (2008/06/13)
A 4-cyclopentenone of the formula: STR1 wherein R is a lower alkyl group, a lower alkenyl group or a lower alkynyl group and R' is a hydroxyl group or an aliphatic acyloxy group, provided that in case of the dl-form, R' is not a hydroxyl group and also that the substituent R at the 2-position and the methyl group at the 3-position take a cis-configuration in the dl-, d- or l-form.
Process for preparing cyclopentenolones
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, (2008/06/13)
A process for preparing cyclopentenolones of the formula STR1 wherein R1 is an alkyl group having not more than 6 carbon atoms, an alkenyl or alkynyl group having not more than 6 carbon atoms or a group of the formula: STR2 in which R2 is a hydrogen atom, a methyl group or a halogen atom directly from the corresponding furan-carbinols of the formula: STR3 wherein R1 is as defined above in a single step with an excellent yield, characterized in that the furan-carbinols are treated with water in the presence or absence of a catalyst.
Process for preparing cyclopentenolones
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, (2008/06/13)
A process for preparing cyclopentenolones in good yields which comprises treating a 4-hydroxy-4-R2 -5-R1 -2-cyclopentenone of the formula: STR1 wherein R1 is an alkyl group having not more than 6 carbon atoms, an alkenyl group having not more than 6 carbon atoms, an alkynyl group having not more than 6 carbon atoms or a group of the formula: STR2 (in which R3 is hydrogen, methyl or halogen) and R2 is a hydrogen atom or a methyl group, provided that when R2 is hydrogen, R1 is neither α-methylallyl nor α-methylpropargyl, in an aqueous medium in the presence or absence of a metal salt at a temperature of 20° to 200° C. to give the corresponding 2-R1 -3-R2 -4-hydroxy-2-cyclopentenone of the formula: STR3 wherein R1 and R2 are each as defined above.
