41301-44-4

Basic information

• Product Name: methyl trans-3-formyl-2,2-dimethylcyclopropanecarboxylate
• Synonyms: methyl trans-3-formyl-2,2-dimethylcyclopropanecarboxylate
• CAS NO: 41301-44-4
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.17908
• EINECS: 255-303-2
• Mol File: 41301-44-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 186.8 °C at 760 mmHg
• Flash Point: 69.2 °C
• Appearance: /
• Density: 1.149 g/cm³
• Vapor Pressure: 0.652mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: methyl trans-3-formyl-2,2-dimethylcyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl trans-3-formyl-2,2-dimethylcyclopropanecarboxylate(41301-44-4)
• EPA Substance Registry System: methyl trans-3-formyl-2,2-dimethylcyclopropanecarboxylate(41301-44-4)

Safety Data

• Hazardous Substances Data: 41301-44-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H12O3/c1-8(2)5(4-9)6(8)7(10)11-3/h4-6H,1-3H3

Upstream product

• 186581-53-3 diazomethane 
• 26771-21-1 (1R,4R,5S)-4-hydroxy-6,6-dimethyl-3-oxabicyclo[3.1.0]hexa-2-one 
• 113323-08-3 (E)-3-[(2S,4S,5R)-4-Methyl-5-phenyl-3-(toluene-4-sulfonyl)-oxazolidin-2-yl]-acrylic acid methyl ester 
• 27335-35-9 (+/-)-(1R,2S)-2-(methoxycarbonyl)-3,3-dimethyl-1-cyclopropanecarboxylic acid 
• 78984-87-9 methyl 4,5-epoxy-3,3-dimethylpentanoate 
• 62222-77-9 cis-3-hydroxymethyl-2,2-dimethylcyclopropane-1-carboxylic acid lactone 
• 7796-72-7 ethyl 3,3-dimethylpent-4-enoate 
• 7796-73-8 3,3-dimethylpent-4-enoic acid 
• 65371-41-7 5-iodomethyl-4,4-dimethyltetrahydrofuran-2-one 
• 29787-21-1 4-isopropylidene-6,6-dimethyl-3-oxa-bicyclo[3.1.0]hexan-2-one 
• 29787-20-0 3,3,6,6-tetramethylbicyclo[3.1.0]hexane-2,4-dione 
• 713-27-9 (+/-)-2,2-Dimethyl-cis-3-(1-oxo-2-hydroxy-2-methyl-propyl)-cyclopropan-1-carbonsaeure 
• 702-50-1 2,2,5,5-tetramethylcyclohexa-1,3-dione 
• 76842-28-9 (1R,3S)-3-Chlorocarbonyl-2,2-dimethyl-cyclopropanecarboxylic acid methyl ester 

Relevant articles and documents

Novel synthesis of (d,l) trans-chrysanthemic acid involving a β-diketone fragmentation

Methyl (d,l) trans-chrysanthemate as well as its cis-diastereoisomer have been prepared from dimethyl dimedone, one of their isomers, in a few steps and with complete control of the relative stereochemistry.

ALLYLIC STEREOCENTRE DIRECTED CYCLOPROPANATION. A NEW HIGHLY ENANTIOSELECTIVE SYNTHESIS OF HEMICARONIC ALDEHYDE

isopropyledenetriphenylphosphorane reacts with oxazolidine 4 with excellent ?-face selectivity.The title compound is obtained in high optical purity after removal of the chiral auxiliary.

A SYNTHESIS OF TRANS- AND CIS-CARONALDEHYDES

A preparation of trans- and cis-caronaldehyde derivatives is described by employing iodolactonization reaction as a key step.Investigation is also carried out to establish an asymmetric synthesis by employing the same methodology which allows diastereoselective formation of optically active intermediates in both enantiomeric forms from a single precursor though the degree of asymmetric induction is found to be less satisfactory.