26771-21-1

Basic information

• Product Name: cis-caronaldehydic acid hemiacetal
• Synonyms: cis-caronaldehydic acid hemiacetal
• CAS NO: 26771-21-1
• Molecular Formula: C₇H₁₀O₃
• Molecular Weight: 142.15
• Mol File: 26771-21-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 292.6°C at 760 mmHg
• Flash Point: 135.8°C
• Appearance: /
• Density: 1.287g/cm³
• Vapor Pressure: 0.000193mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: cis-caronaldehydic acid hemiacetal(CAS DataBase Reference)
• NIST Chemistry Reference: cis-caronaldehydic acid hemiacetal(26771-21-1)
• EPA Substance Registry System: cis-caronaldehydic acid hemiacetal(26771-21-1)

Safety Data

• Hazardous Substances Data: 26771-21-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H10O3/c1-7(2)3-4(7)6(9)10-5(3)8/h3-5,8H,1-2H3

Upstream product

• 67-56-1 methanol 
• 1381843-47-5 C₂₂H₂₄O₇ 
• 1381843-39-5 C₂₂H₂₄O₇ 
• 1381843-06-6 C₂₁H₃₄O₆Si 
• 474429-71-5 C₉H₁₂O₅ 

Downstream Products

• 1381843-18-0 C₂₂H₂₄O₇ 
• 1381843-39-5 C₂₂H₂₄O₇ 
• 1381843-47-5 C₂₂H₂₄O₇ 
• 76740-09-5 (1R,5S) 6,6-dimethyl-4(R)-[(1'S), (2'R), (5'S) 2'-isopropyl-5'-methyl-cyclohexanoxy]-3-oxabicyclo-(3,1,0)-hexan-2-one 
• 84368-72-9 (1S,3R)-2,2-Dimethyl-3-vinyl-cyclopropanecarbonyl chloride 
• 26770-99-0 methyl (+/-)-cis-3-formyl-2,2-dimethyl-1-cyclopropanecarboxylate 

Relevant articles and documents

Efficient resolution of some monoprotected derivatives of Corey lactone

Racemic monoprotected at primary hydroxy group Corey lactones were resolved using (1S,2R,5R)-6,6-dimethyl-4-oxo-3-oxabicyclo-[3.1.0]hexan-2-ol as a chiral auxiliary reagent of hemiacylal chemotype.

A SYNTHESIS OF TRANS- AND CIS-CARONALDEHYDES

A preparation of trans- and cis-caronaldehyde derivatives is described by employing iodolactonization reaction as a key step.Investigation is also carried out to establish an asymmetric synthesis by employing the same methodology which allows diastereoselective formation of optically active intermediates in both enantiomeric forms from a single precursor though the degree of asymmetric induction is found to be less satisfactory.