41307-29-3

Basic information

• Product Name: 2,4-dichloro-7-phenylpyrimido[4,5-d]pyrimidine
• Synonyms: 2,4-dichloro-7-phenylpyrimido[4,5-d]pyrimidine
• CAS NO: 41307-29-3
• Molecular Weight: 277.112
• Mol File: 41307-29-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,4-dichloro-7-phenylpyrimido[4,5-d]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-dichloro-7-phenylpyrimido[4,5-d]pyrimidine(41307-29-3)
• EPA Substance Registry System: 2,4-dichloro-7-phenylpyrimido[4,5-d]pyrimidine(41307-29-3)

Safety Data

• Hazardous Substances Data: 41307-29-3(Hazardous Substances Data)

Upstream product

• 52126-76-8 4-amino-2-phenylpyrimidine-5-carbonitrile 
• 94741-69-2 4-amino-2-chloropyrimidine-5-carbonitrile 
• 98-80-6 phenylboronic acid 

Downstream Products

• 41307-30-6 4,4'-(7-phenylpyrimido[4,5-d]pyrimidin-2,4-diyl)dimorpholine 

Relevant articles and documents

Pyridopyrimidine Or Pyrimidopyrimidine Compound, Prepration Method, Pharmaceutical Composition, And Use Thereof

The present invention belongs to the field of pharmaceutical Chemistry. In particular, the present invention relates to a pyridopyrimidine or pyrimidopyrimidine compound as represented by general formula (I), or an isomer thereof or a pharmaceutically acceptable salt, ester, prodrug or solvate thereof, a preparation method, a pharmaceutical composition and uses thereof in preparing a mTOR inhibitor. As a mTOR inhibitor, the compound or the pharmaceutical composition thereof can be used for treating a disease or condition due to PI3K-AKT-mTOR signalling pathway malfunction.