4132-38-1

Usage

Uses

Used in Pharmaceutical Research:
D-Glucose, 4-O-methylis used as a research compound for studying reversible inhibitors of β-glucosidase, an enzyme that plays a crucial role in the breakdown of complex carbohydrates. This application is significant in understanding the enzyme's function and its potential as a therapeutic target for various diseases, including lysosomal storage disorders and certain cancers.
Used in Biochemical Studies:
In the field of biochemistry, D-Glucose, 4-O-methylserves as an important tool for investigating the specificity and mechanisms of enzymes that act on glucose and other related sugars. By providing a structurally similar yet distinct molecule, researchers can gain insights into enzyme-substrate interactions and the factors that influence these interactions.
Used in Chemical Synthesis:
D-Glucose, 4-O-methylcan also be utilized as a starting material or intermediate in the synthesis of various complex organic compounds, particularly those with potential applications in the pharmaceutical, agrochemical, and materials science industries. The modified glucose molecule can be further functionalized or modified to create novel compounds with specific properties and functions.

Upstream product

• 121965-59-1 O³,O⁶-diacetyl-O⁴-methyl-O¹,O²-phenanthrene-9,10-diyl-ξ-D-glucopyranose 
• 3056-43-7 methyl 4-O-methyl-β-D-glucopyranoside 
• 27551-99-1 methyl 4-O-methyl-α-D-glucopyranoside 
• 4120-73-4 O⁴-methyl-D-glucuronic acid 
• 20702-87-8 2,3-5,6-bis-O-isopropylidene-aldehydo-D-glucose dimethylacetal 
• 74-88-4 methyl iodide 
• 17791-36-5 methyl 2,3-di-O-benzyl-α-D-glucopyranoside 
• 24905-16-6 methyl 4-O-methyl-2,3,6-tri-O-acetyl-β-D-glucoside 
• 6936-67-0 D-Glucose-dibenzyldithioacetal 
• 31505-22-3 β-D-4-O-methylglucopyranoside 

Downstream Products

• 7404-25-3 O⁴-methyl-D-gluconic acid-5-lactone 
• 105579-93-9 benzyl-(O²,O³,O⁶-triacetyl-O⁴-methyl-β-D-glucopyranoside) 
• 1518-54-3 α-isosaccharinic acid 
• 64-18-6 formic acid 
• 94438-34-3 O⁴-methyl-D-arabino-[2]hexosulose-bis-phenylhydrazone 

Relevant academic research and scientific papers

2-C-CARBOXYALDOSES AND ALDONIC ACIDS FROM CELLOBIOSE, MALTOSE, AND 4-O-METHYL-D-GLUCOSE WITH 2-ANTHRAQUINONESULFONIC ACID

Cellobiose, maltose, and 4-O-methyl-D-glucose were treated with 0.1-20mM 2-anthraquinonsulfonic acid in 0.1M sodium hydroxide at 40 deg C.The hydroxy carboxylic acids formed were separated by ion-exchange, and analyzed by g.l.c.-m.s. as their per(trimethylsilyl) derivatives.The acidic oxidation products of cellobiose were further fractionated into aldonic acids and carboxyaldoses by ion-exchange chromatography.The isolated carboxyaldoses were reduced with sodium borohydride, and then analyzed by g.l.c.-m.s. before and after hydrolysis.The O-D-glucosyl- and O-methyl-substituted products of the sugars consisted of erythronic, arabinonic, ribonic, gluconic, and mannonic acids, in addition to 2-C-carboxypentoses.The nonsubstituted products of the reducing D-glucose unit were formic, glycolic, 2-deoxytetronic, and 3-deoxypentonic acids, and 2-C-carboxy-3-deoxypentoses.