41348-33-8

Upstream product

• 108885-08-1 (1S)-(7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester 
• 814-68-6 acryloyl chloride 
• 247078-63-3 (1S,2R)-(7,7-dimethyl-2-hydroxybicyclo[2.2.1]hept-1-yl)methane sulfonic acid phenyl ester 
• 62319-13-5 (1S,4R)-methyl (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonate 

Downstream Products

• 89156-12-7 (1S)-(+)-10-(phenylsulfonyl)isoborneol 
• 13144-52-0 N-Methyl-10-camphersulfonanilid 
• 89156-16-1 (1R,2S,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,4R)-1-benzenesulfonylmethyl-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 89156-16-1 (1S,2S,4S)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,4R)-1-benzenesulfonylmethyl-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 89156-16-1 (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,4R)-1-benzenesulfonylmethyl-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 89156-16-1 (1S,2R,4S)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,4R)-1-benzenesulfonylmethyl-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 89156-14-9 Acrylic acid (1S,2R,4R)-1-benzenesulfonylmethyl-7,7-dimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 554450-42-9 10-phenylsulfonylisobornyl 3-oxo-3-phenyl-2-triphenylphosphoranylidenepropanoate 
• 554450-39-4 (1S)-10-(phenylsulfonyl)isobornyl (triphenylphosphoranylidene)acetate 
• 554450-43-0 10-phenylsulfonylisobornyl 3-azido-2-bromo-3-phenylpropenoate 
• 554450-40-7 10-phenylsulfonylisobornyl chloroacetate 
• 554450-38-3 (1S)-10-(phenylsulfonyl)isobornyl bromoacetate 
• 96303-88-7 (-)-10-dicyclohexylsulfamoyl-D-isoborneol 

Relevant academic research and scientific papers

An improved synthesis of 10-isobornylsultone

A modified and improved synthesis of 10-isobornylsultone in three steps and in 81% overall yield starting from (+)-camphor-10-sulfonic acid is described. The synthesis proceeds via methyl sulfonate ester formation, stereoselective reduction and base-catalysed intramolecular cyclisation.

Synthesis of phenyl 2-acryloyloxybornane-10-sulfonate diastereomers

Several routes to phenyl 2-exo- and 2-endo-acryloyloxybornane-10-sulfonate have been investigated. Preparation of the former product is complicated by concomitant formation of 10-isobornylsultone, while addition of HCl is observed when the alcohol precursors are treated with acryloyl chloride in the presence of Al2O3. An X-ray crystal structure has been determined for one of the chlorinated derivatives.