413577-75-0

Upstream product

• 413577-73-8 [4-(N-benzyloxycarbonylamino)-2-nitronaphthalen-1-yl]acetic acid 
• 2401-85-6 1-chloro-2,4-dinitronaphthalene 
• 413577-71-6 ethyl [4-(N-benzyloxycarbonylamino)-2-nitronaphthalen-1-yl]acetate 
• 897918-36-4 ditert-butyl (4-amino-2-nitronaphthalen-1-yl)-malonate 
• 897918-37-5 (4-amino-2-nitronaphthalen-1-yl) acetic acid 
• 413577-69-2 ethyl (4-amino-2-nitronaphthalen-1-yl)acetate 

Downstream Products

• 897918-34-2 acetic acid 2-(4-benzyloxycarbonylamino-2-nitro-naphthalen-1-yl)-ethyl ester 
• 413577-77-2 2-[4-(N-benzyloxycarbonylamino)-2-nitronaphthalen-1-yl]ethyl chloride 

Relevant academic research and scientific papers

Efficient synthesis of achiral seco-cyclopropylbenz[2,3-e]indoline analogues: [4-Amino-2-(5,6,7-trimethoxyindole-2-carboxamido)naphthalen-1-yl] ethyl chloride and [4-hydroxy-2-(5,6,7-trimethoxyindole-2-carboxamido) naphthalen-1-yl]ethyl chloride

Achiral seco-aminocyclopropylbenz[2,3-e]indoline and seco- hydroxycyclopropylbenz[2,3-e]indoline (seco-CBI) analogues of the duocarmycins and CC-1065, e.g., 7 and 8, are potent anticancer agents. This paper describes significantly improved synthetic strat

Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins

The present invention relates to novel achiral seco-analogues of the DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II III, IV and V: wherein X is a good leaving group, such as a chl

Compositions and methods of the use thereof achiral analogues of CC-1065 and the duocarmycins

The present invention relates to novel achiral seco-analogues of DNA minor groove and sequence-selective alkylating agents (+)-CC1065 and the duocarmycins, depicted as general class I, II, III, IV and V: wherein X is a good leaving group, such as a chlori