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41372-20-7

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Product FOB Price Min.Order Supply Ability Supplier
Apomorphine hydrochloride Manufacturer/High quality/Best price/In stock
Cas No: 41372-20-7
USD $ 3.0-3.0 / Kilogram 1 Kilogram 1-100 Metric Ton/Month Dayang Chem (Hangzhou) Co.,Ltd. Contact Supplier
Factory Price API 99% R-(-)-Apomorphine 41372-20-7 GMP Manufacturer
Cas No: 41372-20-7
USD $ 0.1-0.1 / Gram 1 Gram 100 Metric Ton/Year Xi'an Xszo Chem Co., Ltd. Contact Supplier
R-(-)-Apomorphine CAS 41372-20-7
Cas No: 41372-20-7
USD $ 3.0-10.0 / Kilogram 1 Kilogram 300 Metric Ton/Week Hebei Nengqian Chemical Import and Export Co., LTD Contact Supplier
Manufacturer supply CAS 41372-20-7 with best quality
Cas No: 41372-20-7
USD $ 139.0-210.0 / Kilogram 1 Kilogram 1000 Kilogram/Day Zhuozhou Wenxi import and Export Co., Ltd Contact Supplier
4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (2:2:1), (6aR)-
Cas No: 41372-20-7
No Data No Data 10000 Metric Ton/Month Henan Wentao Chemical Product Co., Ltd. Contact Supplier
R-(-)-Apomorphine CAS:41372-20-7
Cas No: 41372-20-7
No Data 1 Gram 3 Metric Ton/Month Qingdao Beluga Import and Export Co., LTD Contact Supplier
4H-Dibenzo[de,g]quinoline-10,11-diol,5,6,6a,7-tetrahydro-6-methyl-, hydrochloride, hydrate (2:2:1), (6aR)-
Cas No: 41372-20-7
No Data 1 Kilogram 1 Metric Ton/Day Shandong Hanjiang Chemical Co., Ltd. Contact Supplier
R-(-)-Apomorphine
Cas No: 41372-20-7
USD $ 30.0-40.0 / Kilogram 1 Kilogram 100 Metric Ton/Month Hebei Quanhe Biotechnology Co. LTD Contact Supplier
R-(-)-Apomorphine
Cas No: 41372-20-7
No Data No Data 5 Hangzhou J&H Chemical Co., Ltd. Contact Supplier
(R)-Apomorphine Hydrochloride Hemihydrate
Cas No: 41372-20-7
USD $ 100.0-100.0 / Kilogram 1 Kilogram 10000 Kilogram/Day Metric Ton/Day Zibo Hangyu Import&Export Co., Ltd Contact Supplier

41372-20-7 Usage

Description

Apomorphine (41372-20-7) is an archetypal dopamine pan-receptor agonist. Displays anti-Parkinsons activity in vivo.1 Protects against MPTP-induced neurotoxicity in a mouse mode1,2 In clinical use for Parkinson’s disease.4,5

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 41372-20-7 differently. You can refer to the following data:
1. emetic, antiparkinsonian, erextile dysfunction therapy
2. Dopamine (D1 and D2) receptor agonist. Emetic. Antiparkinsonian.
3. R-(?)-Apomorphine hydrochloride hemihydrate is a nonselective dopamine agonist with anti-Parkinsonian and neuroprotective effects in vivo.

Brand name

Apokyn (Vernalis).

Purification Methods

Crystallise the salt from H2O (hemihydrate) and from EtOH. Crystals turn green on exposure to light. (see previous entry). NARCOTIC.

References

1) Merck Index 14:746 2) Millan et al. (2002), Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes; J. Pharmacol. Exp. Therap., 303 791 3) Grunblatt et al. (1999), Apomorphine protects against MPTP-induced neurotoxicity in mice.; Mov. Discord, 14 612 4) Auffret et al. (2017), Apomorphine pump in advanced Parkinson’s disease: Effects on motor and nonmotor symptoms with brain metabolism correlations; J. Neurol. Sci, 372 279 5) Jenner and Katzenschlager (2016), Apomorphine – pharmacological properties and clinical trials in Parkinson’s disease; Parkinsonism. Related. Disord., 33 Suppl. 1:S13

Check Digit Verification of cas no

The CAS Registry Mumber 41372-20-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,7 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41372-20:
(7*4)+(6*1)+(5*3)+(4*7)+(3*2)+(2*2)+(1*0)=87
87 % 10 = 7
So 41372-20-7 is a valid CAS Registry Number.
InChI:InChI=1/2C17H17NO2.2ClH.H2O/c2*1-18-8-7-10-3-2-4-12-15(10)13(18)9-11-5-6-14(19)17(20)16(11)12;;;/h2*2-6,13,19-20H,7-9H2,1H3;2*1H;1H2/t2*13-;;;/m11.../s1

41372-20-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name apomorphine hydrochloride

1.2 Other means of identification

Product number -
Other names R-(?)-Apomorphine hydrochloride hemihydrate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:41372-20-7 SDS

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