41373-99-3Relevant academic research and scientific papers
Facile Synthesis of New [1,2,4]Triazolo[4,3-b]pyridazine
Arghiani,Seyedi,Bakavoli,Eshghi
, p. 1099 - 1107 (2015/08/06)
A number of new [1,2,4]triazolo[4,3-b]pyridazines were prepared by either cyclocondesation of substituted hydrazinopyridazines with orthoesters or oxidative cyclization of their hydrazone analogs in nitrobenzene as an oxidizing agent. A host of other new
Efficient mono- and bis-functionalization of 3,6-dichloropyridazine using (tmp)2Zn·2MgCl2·2LiCl
Wunderlich, Stefan,Knochel, Paul
supporting information; experimental part, p. 6387 - 6389 (2009/04/13)
3,6-Dichloropyridazine undergoes a smooth metallation using (tmp) 2Zn·2MgCl2·2LiCl. The resulting bis-organozinc species react with various electrophiles; subsequent functionalization via a second metallation proceeds readily; further reactions with hydrazine lead to highly substituted pyrazolo[3,4-c]pyridazines derivatives. The Royal Society of Chemistry 2008.
