594838-97-8

Upstream product

• 201230-82-2 carbon monoxide 
• 768-60-5 4-methoxyphenylacetylen 
• 21724-94-7 3-(4-methoxyphenyl)-1-phenyl-1H-pyrrole-2,5-dione 
• 696-62-8 para-iodoanisole 
• 110-17-8 (2E)-but-2-enedioic acid 

Downstream Products

• 41373-99-3 3,6-dichloro-4-(4-methoxy-phenyl)-pyridazine 
• 216227-78-0 4-(4-methoxyphenyl)-5-[(Z)-(4-methoxyphenyl)methylidene]furan-2-one 
• 136762-97-5 4-(4-hydroxyphenyl)-5-[(Z)-(4-hydroxyphenyl)methylidene]furan-2-one 

Relevant academic research and scientific papers

Facile Synthesis of New [1,2,4]Triazolo[4,3-b]pyridazine

A number of new [1,2,4]triazolo[4,3-b]pyridazines were prepared by either cyclocondesation of substituted hydrazinopyridazines with orthoesters or oxidative cyclization of their hydrazone analogs in nitrobenzene as an oxidizing agent. A host of other new

Arylmaleic anhydrides via Heck arylation of fumaric acid

Palladium-catalyzed arylation of fumaric acid with aryl iodides is found to be a very simple, economic and scalable approach to arylmaleic anhydrides. The reaction is facilitated by the presence of donor moieties on the aryl fragment and does not occur wi

High-pressure-assisted addition of (methoxyphenyl)maleic anhydrides to dienes. Synthesis of 3a-aryltetrahydroisoindole-1,3-diones

A new synthesis of (2-and 4-methoxyphenyl)maleic anhydrides was accomplished, the reactions of which with cyclopentadiene and 3-sulfolene, serving as a 1,3-butadiene equivalent, furnished the [4+2]-cycloadducts. The latter were converted into imides of 2-

A facile synthesis of rubrolide E1

A simple and efficient synthesis of rubrolide E (1e) has been demonstrated via Meerwein coupling reaction of para-anisyldiazonium chloride with N-phenylmaleimide (2), regioselective reduction of para-anisylmaleic anhydride (4), Knoevenagel condensation of butyrolactone 5 with para-anisaldehyde and demethylation pathway. Georg Thieme Verlag Stuttgart.

Synthesis of maleic anhydrides and maleic acids by Pd-catalyzed oxidative dicarbonylation of alk-1-ynes

We have found that carbon dioxide effectively promotes the Pd-catalyzed oxidative carbonylation of terminal alkynes to give maleic anhydrides in fair yields. Reactions were carried out in aqueous dioxane at 60-80 °C in the presence of catalytic amounts of PdI2 in conjunction with KI and under a 4:1:10 mixture of CO/air/CO2 (60 atm total pressure at 25 °C). By working in the presence of a large excess of water, maleic acids were formed selectively with unprecedented catalytic efficiencies for this kind of reaction. In the latter case, the use of an excess of carbon dioxide tended to inhibit, rather than promote, the reaction. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.