4142-59-0

Usage

Uses

Used in Pharmaceutical Industry:
2-(TERT-BUTYL)-6-[(DIMETHYLAMINO)METHYL]-4-METHYLBENZENOL is used as an intermediate in the synthesis of various pharmaceuticals for its ability to facilitate the production of complex organic molecules. Its presence in the synthesis process aids in the creation of new drugs and the improvement of existing ones.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(TERT-BUTYL)-6-[(DIMETHYLAMINO)METHYL]-4-METHYLBENZENOL is utilized as a component in the development of pesticides and other agricultural chemicals. Its role in these products helps to enhance their effectiveness and contribute to the overall productivity of the industry.
Used in Plastics and Polymers Manufacturing:
2-(TERT-BUTYL)-6-[(DIMETHYLAMINO)METHYL]-4-METHYLBENZENOL is employed as a high boiling solvent in the production of plastics and polymers. Its properties allow for the efficient processing of these materials, leading to improved product quality and performance.
Used as a Laboratory Reagent:
This organic compound is also used as a laboratory reagent, where it plays a crucial role in various chemical reactions and experiments. Its versatility in the lab setting makes it a valuable tool for researchers and scientists.
Safety Precautions:
It is important to handle 2-(TERT-BUTYL)-6-[(DIMETHYLAMINO)METHYL]-4-METHYLBENZENOL with care, as it can be harmful if swallowed, inhaled, or comes into contact with skin and eyes. Proper safety measures should be taken to minimize the risk of exposure and ensure the well-being of those working with this chemical.

InChI:InChI=1/C14H23NO/c1-10-7-11(9-15(5)6)13(16)12(8-10)14(2,3)4/h7-8,16H,9H2,1-6H3

Upstream product

• 50-00-0 formaldehyd 
• 2409-55-4 2-tert-Butyl-4-methylphenol 
• 124-40-3 dimethyl amine 

Downstream Products

• 1080669-07-3 (2-tert-butyl-4-methyl-6-(N,N-dimethylaminomethyl)phenoxy)triisopropoxidotitanium(IV) 
• 175907-75-2 2-tert-Butyl-4-methyl-6-(2-methylamino-naphthalen-1-ylmethyl)-phenol 

Relevant academic research and scientific papers

Mono(aryloxido)titanium(IV) Complexes and their application in the selective dimerization of ethylene

We report on the synthesis of mono(aryloxido)titanium(IV) complexes of general formula [Ti[O(o-R)Ar]X3), with X = OiPr, ArO = 2-ie.rr-but:yl-4-methylphenoxy and. R = CMe3 (2a), CMe2Ph (2b) and CH2NMe2 (2c). Attempts to reach pure mono(aryloxido) complexes when R = CH2NMe(CH2Ph) (2d) or CH2N(CH2Ph)2 (2e) were unsuccessful, When R = CH2OMe, the analogous mononuclear complex was not obtained, and instead, a dinuclear complex [(2-ieri-butyl-4methyl-6- methoxymethylphenoxy) TiCl(OiPr)(H2-OiPr)2TiCl(OiPr) 2] (3) was formed. Complexes 2b and 3 were characterized by single-crystal X-ray diffraction, The former contains a tetrahedrally coordinated. TiIV centre, whereas in the latter the aryloxido ligand behaves as a chelating-bridging ligand between the two, chemically very different metal centres that form two face-sharing octahedra, Different synthetic approaches starting from. [Ti(OiPr)4] or [TiCl(OiPr) 3] were evaluated and are discussed, The hemllabile behaviour of the aryloxido ligand. resulting from, reversible coordination of its side arm was studied by variable-temperature 1H NMR spectroscopy for 2c (R = CH 2NMe2). Complexes 2a-d were contacted, with ethylene and AlEt3 as cocatalyst, When activated with AlEt3 (3 equiv.) at 20 bar and 60 ° C, complex 2c exhibits interesting activity (2100 g/gTi/h) for the selective dimerization of ethylene to 1-butene (92% C 4"=; 99+% C4=1), Noticeable differences in catalyst activity were observed when the R group was modified,

Synthesis and study of the antiradical activity of substituted hydroxybenzylamines and their hydrogen chloride salts

Different alkylated hydroxybenzylamines and their hydrogen chloride salts were synthesized. The rate constants of their reactions with peroxide radicals k1 and the stoichiometric factors of inhibition f were measured in the initiated oxidation of cumene and methyl oleate. Copyright

Heterocyclic Spirocyclohexadienones from Substituted Phenols

Mannich bases were prepared from substituted phenols with aliphatic amines and formaldehyde.Amine exchange with N-methyl-2-naphthylamine followed by a Hofmann Martius rearrangement gave rise to o,o'-amino-hydroxy-diphenylmethane derivatives.Under cyclization conditions some of these compounds produced spirocyclohexadienones, which are the ipso analogs to the hypothetic intermediates postulated in the aminomethylation mechanism of phenols. - Keywords: Mannich Reaction; Phenol Dienone Tautomerism; Hofmann Martius Rearrangement