Nα-Tosyl-Nδ-tosylglycyl-L-ornithin, also known as Tosyl-Gly-L-Orn, is a synthetic tripeptide that consists of three amino acids: L-ornithine, glycine, and L-ornithine, with tosyl (tosyl = 4-methylbenzenesulfonyl) groups attached to the Nα and Nδ positions of the first and second L-ornithine residues, respectively. Nα-Tosyl-Nδ-tosylglycyl-L-ornithin is often used as a substrate in enzymatic assays, particularly for proteases, due to its specific structure and the presence of the tosyl groups, which can be cleaved by certain enzymes. The tosyl groups serve as a protecting group, allowing for the controlled release of the peptide upon enzymatic action. This tripeptide is also used in the study of protein folding and stability, as well as in the development of new drugs targeting specific proteases.
The CAS Registry Mumber 4143-99-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,4 and 3 respectively; the second part has 2 digits, 9 and 9 respectively. Calculate Digit Verification of CAS Registry Number 4143-99: (6*4)+(5*1)+(4*4)+(3*3)+(2*9)+(1*9)=81 81 % 10 = 1 So 4143-99-1 is a valid CAS Registry Number.