41431-75-8Relevant articles and documents
2-Furanylboronic acid as an effective catalyst for the direct amidation of carboxylic acids at room temperature
Tam, Eric Kwok Wai,Rita,Liu, Lionel Yiqian,Chen, Anqi
, p. 1100 - 1107 (2015/02/19)
2-Furanylboronic acid has been identified as an inexpensive and effective catalyst for the dehydrative amide formation of carboxylic acids and amines. This transformation can be efficiently carried out at room temperature and is applicable to a wide range of carboxylic acids with primary and secondary amines to afford amides in good to excellent yields.
Intramolecular and intermolecular Schmidt reactions of alkyl azides with aldehydes
Lee, Huey-Lih,Aubé, Jeffrey
, p. 9007 - 9015 (2008/02/10)
Despite recent advances in the use of alkyl azides in ring expansion reactions of ketones, there has been little work done on the corresponding chemistry of aldehydes. In the present study, the Lewis acid-promoted reactions of alkyl azides with aldehydes
A comparison of catalysts to promote imidazolide couplings including the identification of 2-hydroxy-5-nitropyridine as a new, safe, and effective catalyst
Dunn, Peter J.,Hoffmann, Wilfried,Kang, Ying,Mitchell, John C.,Snowden, Martin J.
, p. 956 - 961 (2012/12/26)
Five catalysts were compared with respect to their safety and catalytic effectiveness for promoting imidazolide couplings. Reaction rate enhancement, shock sensitivity, and differential scanning calorimetry (DSC) data were considered in this analysis. 6-Chloro-1-hydroxybenzotriazole, which has been described in the literature as a safe catalyst, was found to be shock sensitive. 2-Hydroxy-5-nitropyridine is a new catalyst for this type of reaction and was found to be safe, effective, readily available, and similar in price to that of the 1-hydroxybenzotriazole, a common catalyst for promoting acylation reactions.
