41443-37-2

Basic information

• Product Name: 1H-Pyrazol-3-amine, N,5-diphenyl-
• CAS NO: 41443-37-2
• Molecular Formula: C15H13N3
• Molecular Weight: 235.288
• Mol File: 41443-37-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazol-3-amine, N,5-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazol-3-amine, N,5-diphenyl-(41443-37-2)
• EPA Substance Registry System: 1H-Pyrazol-3-amine, N,5-diphenyl-(41443-37-2)

Safety Data

• Hazardous Substances Data: 41443-37-2(Hazardous Substances Data)

Usage

Structure

Five-membered aromatic ring with two nitrogen atoms at positions 1 and 2, an amino group at position 3, and two phenyl groups attached to nitrogen atoms at positions 1 and 5.

Type

Derivative of pyrazole

Potential applications

Medicinal chemistry and pharmaceutical research due to possible biological activity and interactions with biological systems.

Additional research needed

Further studies are required to explore the compound's potential uses and properties.

Upstream product

• 14901-33-8 Phenylpropiolsaeurethioanilid 
• 81016-31-1 3-anilino-3-methylthio-1-phenylprop-2-en-1-one 
• 302-01-2 hydrazine 
• 1004-22-4 (phenylethynyl)sodium 
• 103-72-0 phenyl isothiocyanate 
• 108-86-1 bromobenzene 
• 92133-94-3 3-phenyl-1-(4-toluenesulfonyl)pyrazol-5-amine 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 104-15-4 toluene-4-sulfonic acid 
• 16516-19-1 O-ethyl 3-oxo-3-phenylpropanethioate 
• 98-86-2 acetophenone 
• 1185994-04-0 5⁽³⁾-(2-bromoanilino)-3⁽⁵⁾-phenyl-1H-pyrazole 

Downstream Products

• 119541-27-4 1,7-diphenyl-3-benzyl-1,2,3,4-tetrahydropyrazolo<1,5-a>triazine 
• 119541-29-6 3-Methyl-1,7-diphenyl-1,2,3,4-tetrahydro-pyrazolo[1,5-a][1,3,5]triazine 
• 119541-30-9 3-(4-Methoxy-phenyl)-1,7-diphenyl-1,2,3,4-tetrahydro-pyrazolo[1,5-a][1,3,5]triazine 
• 119541-28-5 3-Ethyl-1,7-diphenyl-1,2,3,4-tetrahydro-pyrazolo[1,5-a][1,3,5]triazine 

Relevant articles and documents

Pd-Catalyzed N-Arylations of 3-Aryl-1-tosyl-1H-pyrazol-5-amines with Arylbromides and the Migration of Ts Group

An efficient palladium-catalyzed N-arylations of 3-aryl-1-tosyl-1H-pyrazol-5-amines with arylbromides is established. A series of diversified N-arylated products are obtained in excellent yields with broad substrate scope. Importantly, the N-arylated products undergo 1,4- and 1,6-migration reactions of Ts group under the action of Cs2CO3, affording the N-Ts-substituted pyrroles as major products (1,6-migration). Similar results can also be directly obtained by palladium-catalyzed reactions of 3-aryl-1-tosyl-1H-pyrazol-5-amines with arylbromides in the presence of Cs2CO3 as a base. Mechanistic studies reveal that the Ts-migration is achieved through an intermolecular pathway.

Efficient routes to pyrazolo[3,4-b]indoles and pyrazolo[1,5-a] benzimidazoles via palladium- and copper-catalyzed intramolecular C-C and C-N bond formation

(Chemical Equation Presented) Efficient synthetic routes to pyrazolo[3,4-b]indoles and pyrazolo[1,5-a]benzimidazoles via intramolecular palladium- and copper-catalyzed cyclization of 1-aryl/1-unsubstituted 5-(2-bromoanilino)-pyrazole precursors via intram

Synthesis of aminopyrazoles from α- oxoketene O,N-acetals using Montmorillonite K-10/Ultrasound

5(3)-Amino-3(5) phenylpyrazoles 3a-f have been conveniently prepared by condensation of α-oxoketene O,N-acetals 2a-g with hydrazine using montmorillonite K-10 as solid support under sonication.