41445-40-3

Upstream product

• 619-60-3 4-(N,N-dimethylamino)phenol 

Downstream Products

• 198983-68-5 cis-[PtCl₂(tris-(4-dimethylaminophenyl) phosphite)2] 
• 199061-83-1 cis-[PtClMe(tris-(4-dimethylaminophenyl) phosphite)2] 
• 199061-83-1 trans-[PtClMe(tris-(4-dimethylaminophenyl) phosphite)2] 

Relevant academic research and scientific papers

SYNTHESIS OF CEPHALOSPORIN COMPOUNDS

Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction. Provided herein are methods for the synthesis of cephalosporin compounds of formula (I) employing a palladium-catalyzed alkylation reaction, as well as compositions related to the same. In an aspect, provided herein is a method for preparing a compound of formula (II), or a salt thereof, comprising the step of admixing, e.g., reacting, a compound of formula (III), or a salt thereof, with a nucleophile (Nuc) in the presence of reagents comprising: (a) a palladium source; and (b) a palladium-binding ligand, to form a compound of formula (II), or a salt thereof.

Synthesis of fluorescent (benzyloxycarbonylamino)(aryl)methylphosphonates

The synthesis of a library of structurally variable aromatic esters of (benzyloxycarbonylamino)(aryl)methylphosphonic acids is described by means of the Oleksyszyn reaction. The library was enlarged by the application of a Suzuki-Miayra approach and by preparation of mixed esters.