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Z-Arg(NO2G)-OIBC is a chemical compound that consists of a Z-protected arginine residue with a nitro group (NO2) attached to the guanidinium group (G) and an o-iodobenzoic acid (OIBC) moiety. Z-Arg(NO2G)-OIBC is often used in the synthesis of peptides and other biomolecules, particularly in the development of new drugs and pharmaceuticals. The Z-protecting group is a common strategy in peptide synthesis to prevent unwanted side reactions, while the nitro group and o-iodobenzoic acid are used to modulate the chemical properties and reactivity of the molecule. The combination of these functional groups in Z-Arg(NO2G)-OIBC makes it a versatile building block for creating complex molecular structures with specific biological activities.

41446-08-6

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41446-08-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 41446-08-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,4,4 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 41446-08:
(7*4)+(6*1)+(5*4)+(4*4)+(3*6)+(2*0)+(1*8)=96
96 % 10 = 6
So 41446-08-6 is a valid CAS Registry Number.

41446-08-6Relevant academic research and scientific papers

Synthesis of PHI (Peptide Histidine Isoleucine) and Related Peptides and Immunochemical Confirmation of Amino Acid Residue in Position 24 of PHI with use of the Synthetic Peptides

Nokihara, K.,Yanaihara, C.,Iguchi, K.,Fukata, S.,Tanaka, M.,et al.

, p. 7909 - 7916 (1984)

An immunochemical approach, using synthetic peptides, was employed to establish the nature of residue 24 in the amino acid sequence of PHI (peptide histidine isoleucine).PHI(20-27) and 24>-PHI(20-27) were synthesized by conventional solutio

SYNTHETIC APPROACHES FOR THYMOPENTIN (TP-5) USING THE "IN SITU" SILYLATION STRATEGY WITH TRIMETHYLSILYL CYANIDE

Becu, Fr.,Becu, Chr.,Anteunis, M. J. O.

, p. 15 - 23 (2007/10/02)

The synthesis of the pentapeptide TP-5 has been considered as a test case for the "in situ" silylating strategy, using trimethylsilyl cyanide, because of the nature of the involved residues.Thus orthogonal lateral protections for Arg, Lys and Asp are need

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