41456-52-4

Usage

Uses

Used in Chemical Synthesis:
3-Chloro-N,2-dimethylaniline is used as an intermediate in the chemical synthesis industry for the production of dyes and pharmaceuticals. Its unique structure allows for the creation of a variety of complex organic compounds, making it a valuable component in the synthesis process.
Used in Organic Chemistry Reactions:
In the field of organic chemistry, 3-Chloro-N,2-dimethylaniline serves as a reagent, facilitating various chemical reactions. Its presence can influence the outcome of reactions, enabling the formation of desired products and aiding in the advancement of organic chemistry research and development.
Used in Pharmaceutical Development:
3-Chloro-N,2-dimethylaniline is utilized in the pharmaceutical industry as a precursor for the synthesis of certain drugs. Its role in the development of new medications is significant, as it can contribute to the creation of compounds with specific therapeutic properties.
Used in Dye Manufacturing:
In the dye manufacturing industry, 3-Chloro-N,2-dimethylaniline is employed as a key intermediate for the production of various dyes. Its chemical properties make it suitable for the synthesis of dyes with specific color characteristics and stability.

Upstream product

• 70289-22-4 N-(3-Chlor-2-methyl-anilinomethyl)-succinimid 
• 87-60-5 3-chloro-2-methylbenzenamine 
• 71862-02-7 N-(3-chloro-2-methylphenyl)formamide 
• 313545-20-9 (3-chloro-2-methylphenyl)boronic acid 
• 75-52-5 nitromethane 
• 72290-16-5 3-Chlor-N-ethoxycarbonyl-2-methylanilin 

Downstream Products

• 129146-50-5 N-(3'-chloro-2'-methylphenyl)-N-methyl-3-phenylpropenamide 
• 1295605-57-0 C₁₇H₁₇BrClN₃O₂ 
• 1295605-91-2 C₁₆H₁₄ClN₃O₂ 
• 1073265-77-6 N₃-(3-chloro-2-methylphenyl)-N₁-(4-chlorobenzyl)-4-methoxy-N₃-methylbenzene-1,3-disulfonamide 
• 1236266-14-0 4,6-dichloro-N-(3-chloro-2-methylbenzyl)-1,3,5-triazin-2-amine 

Relevant academic research and scientific papers

P(III)/P(V)-Catalyzed Methylamination of Arylboronic Acids and Esters: Reductive C-N Coupling with Nitromethane as a Methylamine Surrogate

The direct reductive N-arylation of nitromethane by organophosphorus-catalyzed reductive C-N coupling with arylboronic acid derivatives is reported. This method operates by the action of a small ring organophosphorus-based catalyst (1,2,2,3,4,4-hexamethylphosphetane P-oxide) together with a mild terminal reductant hydrosilane to drive the selective installation of the methylamino group to (hetero)aromatic boronic acids and esters. This method also provides for a unified synthetic approach to isotopically labeled N-methylanilines from various stable isotopologues of nitromethane (i.e., CD3NO2, CH315NO2, and 13CH3NO2), revealing this easy-to-handle compound as a versatile precursor for the direct installation of the methylamino group.

1,7-palladium migration via C-H activation, followed by intramolecular amination: Regioselective synthesis of benzotriazoles

A novel 1,7-palladiummigration-cyclization-dealkylation sequence for the regioselective synthesis of benzotriazoles has been developed. These reactions proceed in excellent yields with high regioselectivities. The mechanism of the reaction has also been investigated.

DISULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION

There is provided compounds of formula (I), wherein Y1, Y2, Y3, Y4, T1, T2, W1, W2, R1 and R2 have meanings given in the description, and pharmac

HIV REVERSE TRANSCRIPTASE INHIBITORS

Compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein T is O or S; U is O, S, N(R4), or a direct bond linking V to the C(=T) moiety; V is optionally substituted C1-6 alkylene; W is C(O)N(R5) or a direct bond linking V to R3; and R1, R2, R3, R4 and R5 are defined herein. The compounds of Formula (I) and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.

Relaxation Processes in Aromatic Methyl Groups. II. Methyl-Methyl Nuclear Overhauser Enhancements

A range of compounds with methyl groups disposed ortho and peri on heteroaromatic frameworks have been prepared, and T1 values and methyl-methyl Overhauser effects measured for them.Most of the n.O.e. values were 6percent, but two examples o