41469-70-9

Basic information

• Product Name: N-(tert-butyl)-N'-tosylacetimidamide
• Synonyms: N-(tert-butyl)-N'-tosylacetimidamide
• CAS NO: 41469-70-9
• Molecular Weight: 268.38
• Mol File: 41469-70-9.mol

Chemical Properties

• CAS DataBase Reference: N-(tert-butyl)-N'-tosylacetimidamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(tert-butyl)-N'-tosylacetimidamide(41469-70-9)
• EPA Substance Registry System: N-(tert-butyl)-N'-tosylacetimidamide(41469-70-9)

Safety Data

• Hazardous Substances Data: 41469-70-9(Hazardous Substances Data)

Upstream product

• 119072-55-8 tert-butylisonitrile 
• 21849-40-1 dibromamine-T 
• 75-05-8 acetonitrile 

Relevant articles and documents

Unprecedented 1,3-: Tert -butyl migration via the C-N single bond scission of isonitrile: An expedient metal-free route to N -sulfonyl amidines

An unprecedented 1,3-migration of the tert-butyl group was observed while reacting tert-butyl isonitrile with N,N-dibromoaryl sulfonamides and nitrile. The reaction involves the simultaneous C-N single bond scission of isonitrile and the migration of the tert-alkyl group to the adjacent unsaturated nitrogen centre of the nitrile precursor, which eventually results in the formation of N-sulfonyl amidine. This method constitutes a new route for sulfonyl amidine, which does not rely on transition metals. The protocol exhibits a significant advantage in terms of substrate scope and additionally offers an easy synthesis route to guanidine molecules.