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N-iodo-bis-(trimethylsilyl)amine, also known as NIS, is a chemical compound with the formula (Me3Si)2N-I. It is a colorless, hygroscopic liquid that is sensitive to light and air. NIS is widely used as a reagent in organic synthesis, particularly in the formation of carbon-iodine bonds and as a source of electrophilic iodine. It is also employed in the synthesis of various organic compounds, such as iodoalkanes, iodoarenes, and iodonium salts. Due to its reactivity, NIS is typically stored under an inert atmosphere and used in a controlled manner to prevent unwanted side reactions.

4148-00-9

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4148-00-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 4148-00-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,4 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4148-00:
(6*4)+(5*1)+(4*4)+(3*8)+(2*0)+(1*0)=69
69 % 10 = 9
So 4148-00-9 is a valid CAS Registry Number.

4148-00-9Downstream Products

4148-00-9Relevant academic research and scientific papers

Reversible Ligand-Centered Reduction in Low-Coordinate Iron Formazanate Complexes

Broere, Dani?l L. J.,Mercado, Brandon Q.,Lukens, James T.,Vilbert, Avery C.,Banerjee, Gourab,Lant, Hannah M. C.,Lee, Shin Hee,Bill, Eckhard,Sproules, Stephen,Lancaster, Kyle M.,Holland, Patrick L.

, p. 9417 - 9425 (2018)

Coordination of redox-active ligands to metals is a compelling strategy for making reduced complexes more accessible. In this work, we explore the use of redox-active formazanate ligands in low-coordinate iron chemistry. Reduction of an iron(II) precursor occurs at milder potentials than analogous non-redox-active β-diketiminate complexes, and the reduced three-coordinate formazanate-iron compound is characterized in detail. Structural, spectroscopic, and computational analysis show that the formazanate ligand undergoes reversible ligand-centered reduction to form a formazanate radical dianion in the reduced species. The less negative reduction potential of the reduced low-coordinate iron formazanate complex leads to distinctive reactivity with formation of a new N?I bond that is not seen with the β-diketiminate analogue. Thus, the storage of an electron on the supporting ligand changes the redox potential and enhances certain reactivity.

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