41481-20-3Relevant academic research and scientific papers
METHOD FOR THE PRODUCTION OF 4,4'-[1-TRIFLUOROMETHYL)ALKYLIDENE]-BIS-(2,6-DIPHENYLPHENOLS)
-
Page/Page column 9, (2010/12/29)
The present invention relates to a process for preparing 4,4′-[1-(trifluoromethyl)alkylidene]bis(2,6-diphenylphenols), in particular for preparing 4,4′-[1-(trifluoromethyl)ethylidene]bis(2,6-diphenylphenol), which comprises the self-condensation of cyclohexanone in the presence of a basic catalyst to form tricyclic condensation products, dehydrogenation of the resulting tricyclic condensation products in the presence of a supported transition metal catalyst in the condensed phase to form 2,6-diphenylphenol and reaction of the 2,6-diphenylphenol with a trifluoromethyl ketone. The invention further provides an improved process for preparing 2,6-diphenylphenol by aldol self-condensation of cyclohexanone.
Interannular Diastereoselectivity in the Hydroboration of Functionalized 1-Cyclohexylcyclohexenes
Bell, Thomas W.,Vargas, J. Ramon,Crispino, Gerard A.
, p. 1978 - 1987 (2007/10/02)
The reactions of thexylborane with 2-(1-cyclohexen-1-yl)cyclohexanone, cis-2,6-di(1-cyclohexen-1-yl)cyclohexanone, and related alcohols and ketals were investigated.All reactions are selective for products with erythro linkages between cyclohexyl rings, diastereoselectivities ranging from 66 to 97percent.Greatest erythro selectivities were observed for equatorial homoallylic alcohols and ethylene ketals.The configurations of all products were unambiguously assigned by correlation with -2,2'-diones and an erythro, erythro triketone (25), the configuration of which was determined by X-ray crystallography.The diastereoselectivities of these hydroborations and related examples from the literature can be qualitatively rationalized by the Houk transition structure model.
