41531-82-2Relevant academic research and scientific papers
Visible-Light-Mediated Rose Bengal-Catalyzed α-Hydroxymethylation of Ketones with Methanol
Yang, Jingya,Xie, Dongtai,Zhou, Hongyan,Chen, Shuwen,Duan, Jiaokui,Huo, Congde,Li, Zheng
supporting information, p. 3471 - 3476 (2018/09/12)
A visible-light-mediated α-hydroxymethylation of ketones using methanol as the hydroxymethylating reagent has been developed. Using 1 mol% rose bengal as the photosensitizer and air as the green oxidant, the reactions proceeded smoothly at room temperature. Experimental studies indicate the reaction proceeded via a radical pathway. (Figure presented.).
Scandium(Iii) fluoride as a novel catalyst for hydroxymethylation of dimethylsilyl enolates in aqueous media
Kokubo, Masaya,Kobayashi, Shu
experimental part, p. 1562 - 1564 (2009/04/07)
Hydroxymethylation of dimethylsilyl (DMS) enolates using aqueous formaldehyde solution is catalyzed by scandium(III) fluoride (ScF3) in aqueous media to give the corresponding β-hy-droxy ketones in good to excellent yields. Whilst the DMS enola
Lewis acid catalysis in water with a hydrophilic substrate: Scandium-catalyzed hydroxymethylation with aqueous formaldehyde in water
Kokubo, Masaya,Ogawa, Chikako,Kobayashi, Shu
supporting information; experimental part, p. 6909 - 6911 (2009/04/06)
(Chemical Equation Presented) Synthesis in deep water: For the title reaction, which proceeds with high selectivities, acid-base interactions between the Sc catalyst and HCHO are important. The reaction was used in the synthesis of an odorant to demonstra
