41547-82-4

Basic information

• Product Name: Adenosine-15N
• Synonyms: Adenosine-15N
• CAS NO: 41547-82-4
• Molecular Formula: C₁₀H₁₃N₅O₄
• Molecular Weight: 267.24132
• Product Categories: Isotope Labelled Compounds, Nucleotides, Bases & Related Reagents
• Mol File: 41547-82-4.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Water (Slightly, Sonicated)
• CAS DataBase Reference: Adenosine-15N(CAS DataBase Reference)
• NIST Chemistry Reference: Adenosine-15N(41547-82-4)
• EPA Substance Registry System: Adenosine-15N(41547-82-4)

Safety Data

• Hazardous Substances Data: 41547-82-4(Hazardous Substances Data)

Usage

Chemical Properties

Light Yellow Solid

Uses

Nitrogen 15 labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.

Upstream product

• 2004-06-0 6-Chloropurine riboside 
• 157640-50-1 6-N⁶-Benzyl(6-⁽¹⁵⁾N)adenosine 

Downstream Products

• 197227-85-3 (15-NH2)-adenosine N1-oxide 

Relevant articles and documents

Binding of an Acetic Acid Ligand to Adenosine: A Low-Temperature NMR Study

Binding of an acetic acid (HAc) ligand to adenosine (A) was studied by 1H NMR spectroscopic techniques. Using a low-melting deuterated Freon mixture as solvent, liquid-state measurements could be performed in the slow exchange regime and allowe

Studies of the mechanisms of adduction of 2'-deoxyadenosine with styrene oxide and polycyclic aromatic hydrocarbon dihydrodiol epoxides

The mechanism of adduction of 2'-deoxyadenosine by styrene oxide and polycyclic aromatic hydrocarbon dihydrodiol epoxides has been explored using 15N6-labeled adenine nucleosides. The extent of reaction at N1 versus N6 was

Use of a 13C atom to differentiate two 15N-labeled nucleosides

We report the first examples of the specifically 15N and 13C multilabeled nucleosides: [1,NH2-15N2]- and [2-13C-1,NH2-15N2-]- guanosine; [1,7,NH2-15N3]- and [2-13C-1,7,NH2-15N3]-2'- deoxyguanosine. In each set, the [13C] atom functions as a 'tag' that allows the N1 and N2 15N atoms of two 15N-labeled guanines to be unambiguously differentiated in RNA and DNA fragments. The syntheses employ high-yield reactions in which protecting groups are not required and use relatively low cost sources of isotopes: [15N]-ammonium chloride and [15N]- or [13C,15N]-potassium cyanide.