415693-37-7Relevant academic research and scientific papers
Synthesis, X-Ray crystal structure and spectroscopic properties of 1,2,3,4-tetrahydro-2-(thenyl)-3-(N-thenylidine)-4-oxoquinazoline
Naskar, Sumita,Naskar, Subhendu,Blake, Alexander J.,Tadesse, Haregewine,Chattopadhyay, Shyamal Kumar
, p. 986 - 990 (2011)
The Schiff base formed between anthraniloyl hydrazide and thiophen-2-aldehyde is synthesized. Reaction of this Schiff base with VOSO 4 in methanol at room temperature does not yield the expected vanadium complex; instead, the Schiff base is transformed to 1,2,3,4-tetrahydro-2-(thenyl)-3-(N-thenylidine)-4-oxoquinazoline, which has been characterized by elemental analyses and by LC-MS, i.r., n.m.r. and electronic spectroscopies. The X-ray crystal structure of the quinazoline product is reported. The compound crystallizes with monoclinic (P21/n) space group, and the cell parameters are: a = 5.9442(7) A, b = 13.6357(15) A, c = 19.455(2) A, β = 90.499(2)°. The oxo-quinazoline product is found to be luminescent when excited at its lowest energy transition.
Green synthesis and corrosion inhibition study of 2-amino-: N ′-((thiophen-2-yl)methylene)benzohydrazide
Singh,Thakur,Pani,Singh
, p. 2113 - 2124 (2018)
2-Amino-N′-((thiophen-2-yl)methylene)benzohydrazide (ATMBH) was synthesized by a conventional method, as well as by microwave (MW) irradiation. The MW assisted synthesis of ATMBH was found to have good yield and was more eco-friendly compared to the conve
Synthesis and investigation of antimicrobial activity of some nifuroxazide analogues
Alsaeedi, Huda S.,Aljaber, Nabila A.,Ara, Ismet
, p. 3639 - 3646 (2015/12/26)
A series of nifuroxazide analogues [(2a-2e)-(10a-10f)] have been synthesized, structurally identified and tested for antimicrobial activity against a panel of bacteria (Gram-positive and Gram-negative) and the yeast-like pathogenic fungus Candida albicans. The most active compound in this series was 4-amino-benzoic acid (5-nitro-furan-2-ylmethylene)-hydrazide (2b) and 2-amino-benzoic acid (5-nitrofuran-2-ylmethylene)-hydrazide (2d). Furthermore, compounds (9a-9g) and (10a-10g) recorded no activity against selected species except compounds (9f) and (10f) suggesting that using furoic hydrazide and the corresponding hydrazide of thiophene did not improve the antimicrobial activities for this type of compounds. Regarding the activity against Candida albicans, all compounds showed no activity with an exception of substituted nitro furan (2a-2d).
