41580-74-9

Usage

Structure

Benzene derivative with a butynyl group and a methoxy group

Explanation

The compound is derived from benzene, which is a six-carbon ring with alternating single and double bonds. A butynyl group (but-2-yn-1-yl) is attached to the oxygen atom, and a methoxy group (-OCH3) is attached to the benzene ring.

Explanation

The butynyl group contains a triple bond between two carbon atoms, while the methoxy group is an ether with a single oxygen atom connected to a methyl group (-CH3).

Explanation

Due to its unique structure and reactivity, 1-(but-2-yn-1-yloxy)-4-methoxybenzene is used as a starting material for the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals.

Explanation

The compound's specific functional groups and structure make it a versatile intermediate, allowing chemists to create more complex molecules through various chemical reactions.

Explanation

The compound's properties and reactivity make it a promising candidate for the development of new materials and pharmaceutical products, as it can be used to create a wide range of molecules with different applications.

Explanation

Chemists and researchers in different fields, such as pharmaceuticals, materials science, and agrochemicals, are interested in studying and utilizing 1-(but-2-yn-1-yloxy)-4-methoxybenzene due to its potential applications and unique properties.

Functional Groups

Butynyl, Methoxy

Applications

Building block in organic synthesis

Reactivity

Valuable intermediate in the synthesis of complex molecules

Potential Uses

Development of new materials and pharmaceutical products

Interest to Researchers

Various fields of science and industry

Upstream product

• 17061-86-8 1-methoxy-4-(2-propynyloxy)benzene 
• 150-76-5 4-methoxy-phenol 
• 3355-28-0 1-Bromo-2-butyne 
• 74-88-4 methyl iodide 

Downstream Products

• 1262325-87-0 1-(buta-1,3-dien-2-yloxy)-4-methoxybenzene 
• 146306-74-3 cis-(γ-Methyl-allyl)-(4-methoxy-phenyl)-aether 

Relevant academic research and scientific papers

Preparation method and application of propyne aryl ether compound

The invention particularly relates to a method for preparing propyne aryl ether compounds from aryl phenol, halogenated propyne and derivatives of the halogenated propyne, and belongs to the technical field of preparation of the propyne aryl ether compoun

Indium-catalyzed intramolecular hydroarylation of aryl propargyl ethers

Indium(iii) halides catalyze efficiently the intramolecular hydroarylation (IMHA) of aryl propargyl ethers. The reaction proceeds regioselectively with terminal and internal alkynes bearing electron-rich and electron-deficient substituents in the benzenes

Gold nanoparticles supported on TiO2 catalyse the cycloisomerisation/oxidative dimerisation of aryl propargyl ethers

Gold nanoparticles supported on TiO2 (～1%) catalyse in high yields the selective cycloisomerisation of aryl propargyl ethers into the corresponding 2H-chromenes, under heterogeneous conditions. 2H,2′H-3, 3′-Bichromenes resulting from a catalytic oxidative dimerization pathway are also formed as by-products. The Royal Society of Chemistry 2011.

Ph3PAuNTf2 as a superior catalyst for the selective synthesis of 2H-chromenes: Application to the concise synthesis of benzopyran natural products

Ph3PAuNTf2 (≈1 mol-%) catalyzes the selective cycloisomerization of substituted aryl propargyl ethers into 2H-chromenes in excellent yields. Benzofuran byproducts are formed only in the case of electron-deficient arenes, in up to 7% relative yield. The Ph 3PAuNTf2-catalyzed cyclization of aryl propargyl ethers was applied as a key step to the concise synthesis of the naturally occurring benzopyrans seselin, xanthyletin, precocenes I and II, 8-(3′,3′- dimethylallyl)wenteria chromene, and 2,2-dimethyl-8-prenylchromene-6-propenoic acid. Ph3PAuNTf2 is a general, highly efficient, and product-selective catalyst for the clean synthesis of 2H-chromenes from the cycloisomerization of aryl propargyl ethers.The Ph3PAuNTf 2-catalyzed cyclization was applied as a key step in the synthesis of several benzopyran-bearing naturally occurring substances. Copyright

A hierarchy of aryloxide deprotection by boron tribromide

Aryl propargyl ethers and esters are cleaved selectively in the presence of aryl methyl ethers and esters by boron tribromide in dichloromethane. Under the same conditions, allyl ethers undergo very rapid Claisen rearrangement, and benzyl ethers are also cleaved more rapidly than propargyl. A mechanism involving intramolecular delivery of bromide to the propargyl terminus is proposed.