415927-53-6

Basic information

• Product Name: 4-[(4aS,8aR)-4-(3,4-Diethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl]-benzoic acid
• CAS NO: 415927-53-6
• Molecular Weight: 434.492
• Mol File: 415927-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[(4aS,8aR)-4-(3,4-Diethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl]-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(4aS,8aR)-4-(3,4-Diethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl]-benzoic acid(415927-53-6)
• EPA Substance Registry System: 4-[(4aS,8aR)-4-(3,4-Diethoxy-phenyl)-1-oxo-4a,5,8,8a-tetrahydro-1H-phthalazin-2-yl]-benzoic acid(415927-53-6)

Safety Data

• Hazardous Substances Data: 415927-53-6(Hazardous Substances Data)

Upstream product

• 619-67-0 4-Hydrazinobenzoic acid 
• 380227-23-6 cis-(+)-6-(3,4-diethoxybenzoyl)cyclohex-3-enecarboxylic acid 
• 935-79-5 cis-1,2,3,6-tetrahydrophthalic anhydride 
• 2050-46-6 1,2-diethoxybenzene 

Relevant articles and documents

Novel selective phosphodiesterase (PDE4) inhibitors. 4. Resolution, absolute configuration, and PDE4 inhibitory activity of cis-tetra- and cis-hexahydrophthalazinones

Recently, we reported that 4-catechol-substituted cis-(±)-4a,5,6,7,8,8a-hexa- and cis-(±)- 4a,5,8,8a-tetrahydro-2H-phthalazin-1-ones show potent inhibition of phosphodiesterase (PDE4) activity, while the corresponding trans racemic mixtures exhibit only w