415934-29-1

Upstream product

• 39743-20-9 1-(3-chloropropyl)pyrrolidine 
• 540-38-5 p-Iodophenol 

Downstream Products

• 934840-41-2 2-[2-(tert-butyldimethylsilanyloxy)ethyl]-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1H-indole 
• 934840-25-2 2-cyclopropyl-1-[4-(3-pyrrolidin-1-ylpropoxy)phenyl]-1H-indole 
• 1394862-56-6 1,3-bis(2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)oxazol-5-yl)benzene 

Relevant academic research and scientific papers

INDOLE DERIVATIVES AS HISTAMINE 3 RECEPTOR INHIBITORS FOR THE TREATMENT OF COGNITIVE AND SLEEP DISORDERS, OBESITY AND OTHER CNS DISORDERS

This invention relates to compounds having pharmacological activity, to compositions containing these compounds, and to a method of treatment employing the compounds and compositions. More particularly, this invention concerns certain indole derivatives and their salts and solvates. These compounds have H3 histamine receptor antagonist activity. This invention also relates to pharmaceutical compositions containing these compounds and to a method of treating disorders in which histamine H3 receptor blockade is beneficial.