41594-17-6

Upstream product

• 103-71-9 phenyl isocyanate 
• 925669-95-0 2,3-cis-epoxybutane 
• 132783-14-3 cis-2-(phenylimino)-4,5-dimethyl-1,3-dioxolane 
• 21490-63-1 2,3-trans-epoxybutane 
• 109632-71-5 trans-4,5-tetramethylene-2-(phenylimino)-1,3-dioxolane 
• 132783-13-2 trans-2-(phenylimino)-4,5-dimethyl-1,3-dioxolane 

Relevant academic research and scientific papers

Stereocontrolled Oxazolidinone Formation by the Addition of 4,5-Disubstituted Iminodioxolane to Oxirane via a Spiro Compound

4,5-Disubstituted 2-imino-1,3-dioxolanes readily add to oxiranes in the presence of AlCl3, furnishing 1,3-oxazolidin-2-ones in a stereospecific manner, where the configurations of oxiranes and iminodioxolanes are responsible for the configuration of products and the feasibility of the addition, respectively.A preliminary adduct, a spiro compound intermediate, is isolated, and its decomposition to oxazolidinone is demonstrated.

Stereospecific Cycloaddition of Heterocumulenes to Oxiranes Catalyzed by Organotin Halide Complexes

Stereospecific cycloaddition of 2,3-disubstituted oxiranes to heterocumulenes, including carbodiimides, isocyanates and carbon dioxide, is catalytically promoted by dialkyltin diiodide-hexamethylphosphoric triamide (HMPA) system, producing various five-membered heterocycles, where the configuration of the carbons in the oxirane ring is retained.In particular, the addition of isocyanates to oxiranes gave stereospecifically two types of products, dioxolan-2-imines and oxazolidin-2-ones independently, while the rearrangement of the former to the latter product has been already proposed.