41597-55-1Relevant articles and documents
Selective Isomerization via Transient Thermodynamic Control: Dynamic Epimerization of trans to cis Diols
Macmillan, David W. C.,Oswood, Christian J.
supporting information, p. 93 - 98 (2022/01/03)
Traditional approaches to stereoselective synthesis require high levels of enantio- and diastereocontrol in every step that forms a new stereocenter. Here, we report an alternative approach, in which the stereochemistry of organic substrates is selectivel
Ring opening of epoxides with NaHSO4: isolation of β-hydroxy sulfate esters and an effective synthesis for trans-diols
Cavdar, Huseyin,Saracoglu, Nurullah
experimental part, p. 985 - 989 (2009/04/07)
Sodium hydrogen sulfate (NaHSO4) was observed to be highly effective as a reagent or catalyst in the ring-opening reactions of epoxides under mild conditions. Reaction of epoxides with NaHSO4 gave isolable β-hydroxy sulfate esters and vicinal diols. Experimenting with different epoxides, the study investigated the scope of the ring-opening reaction.
Chemistry of anti- and syn-1,2:3,4-Naphthalene Dioxides and Their Potential Relevance as Metabolic Intermediates
Tsang, Wing-Sum,Griffin, Gary W.,Horning, M. G.,Stillwell, W. G.
, p. 5339 - 5353 (2007/10/02)
The reactivity, site of attack, and stereochemistry of reactions of a variety of nucleophiles with the anti- and syn-1,2:3,4-naphthalene dioxides have been explored.In most cases, substituted tetrahydronaphthalene products arising through attack at the C-1 and C-4 positions in the anti mode were obtained.These isomeric dioxides provide excellent precursors for a number of difficultly accessible 1,4-disubstituted naphthalene derivatives such as 1,4-diphenoxynaphthalene and 1,4-dicyanonaphthalene.Evidence is also presented that anti-naphthalene dioxide constitutes an intermediate metabolite in the rat.
