415974-45-7Relevant academic research and scientific papers
STEROIDAL COMPOUNDS AS STEROID SULPHATASE INHIBITORS
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Page/Page column 70-71, (2008/06/13)
There is provided a compound having Formula (I): wherein G is a fluorocarbyl group, and wherein R1 is any one of a sulphamate group, a phosphonate group, a thiophosphonate group, a sulphonate group or a sulphonamide group, capable of inhibiting
D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase
Fischer, Delphine S.,Woo, L. W. Lawrence,Mahon, Mary F.,Purohit, Atul,Reed, Michael J.,Potter, Barry V. L.
, p. 1685 - 1700 (2007/10/03)
A series of novel D-ring modified derivatives of estrone was synthesized and tested as inhibitors of steroid sulfatase (STS). The steroidal D-ring was cleaved via an iodoform reaction and thermal condensation of the resulting marrianolic acid derivative g
