415974-55-9Relevant academic research and scientific papers
D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase
Fischer, Delphine S.,Woo, L. W. Lawrence,Mahon, Mary F.,Purohit, Atul,Reed, Michael J.,Potter, Barry V. L.
, p. 1685 - 1700 (2007/10/03)
A series of novel D-ring modified derivatives of estrone was synthesized and tested as inhibitors of steroid sulfatase (STS). The steroidal D-ring was cleaved via an iodoform reaction and thermal condensation of the resulting marrianolic acid derivative g
