41599-44-4Relevant academic research and scientific papers
Stereochimie de l'addition-1,4 d'enethiolates de dithioesters aux methyl cyclohexene-2 ones
Berrada, Said,Metzner, Patrick
, p. 817 - 821 (2007/10/02)
Lithium dithioacetate, generated by deprotonation with LDA in THF, has been submitted to the action of four methyl 2-cyclohexenones 5-8.Regioselective 1,4-addition has been observed.The two stereoisomeric oxodithioesters of each couple 9-13 have been dist
STEREOCHEMISTRY OF THE C3 ADDITION OF 1-LITHIO 1,1-BIS METHYLSELENOALKANES TO METHYL CYCLOHEXENONES
Lucchetti, J.,Krief, A.
, p. 1623 - 1626 (2007/10/02)
The presence of DME or HMPT allows the C3 regio and stereoselective introduction of 1,1-bis methylselenoalkanes to methyl cyclohexenones.The resulting compounds have been stereoselectively transformed to 3-ethyl methyl cyclohexanones.
EFFETS DE SUBSTITUANTS EN SERIE DIALKYL-1,2 CYCLOHEXANIQUE-I. PERTURBATIONS CONFORMATIONNELLES INDUITES PAR LES INTERACTIONS STERIQUES ENTRE GROUPEMENTS VOISINS
Pons, A.,Chapat, J.P.
, p. 2219 - 2224 (2007/10/02)
The equilibration of the cis and trans isomers of four epimeric pairs of 3,4-dialkyl cyclohexanones (alkyl = Me,Et) have been studied quantitatively at different temperatures.The thermodynamic constants ΔH and ΔS exhibit considerable variations depending on the nature (Me or Et) of the substituents.These quantities were also calculated from statistical considerations.Theoretical and experimental values are in agreement.The origin of the observed variation an increase of the diaxial conformer proportion due to enhanced steric hindrance in other possible conformers when a methyl group is substituted by an ethyl group.This was confirmed experimentally by an NMR study of the trans-3,4-dialkyl cyclohexanone oximes.
