26262-37-3

Upstream product

• 6161-68-8 3-ethyl-4-methyl-anisole 
• 30466-33-2 5-Methyl-2,6-octanedione 
• 51425-53-7 (E)-3-[(trimethylsilyl)oxy]pent-2-ene 
• 20030-29-9 2,3,6-trimethyl-cyclohex-2-en-1-one 
• 78-94-4 methyl vinyl ketone 
• 96-22-0 pentan-3-one 
• 2543-57-9 1-Dimethylamino-3-butanon 
• 6975-85-5 1-methoxybutan-3-one 
• 51425-54-8 (Z)-3-trimethylsiloxy-2-pentene 
• 1007476-32-5 sodium ethyl acetylacetate enolate 
• 3670-64-2 trimethyl-(2-methyl-3-oxo-pentyl)-ammonium; iodide 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 6161-67-7 3-ethyl-4-methyl-phenol 
• 5114-48-7 4-Methyl-3-ethyl-6-hydroxymethylen-cyclohexen-⁽²⁾-on-⁽¹⁾ 
• 41500-87-2 ethyl-3 methyl-4 cyclohexanone trans 

Relevant academic research and scientific papers

NOUVELLE METHODE D'ANNELATION PAR L' INTERMEDIAIRE DE DICETONES-1,5

A new method for six-membered ring annelation is described which involved reaction of hemiacetal vinylogs 1 with silyl enol ethers 2 in the presence of a Lewis acid.

1,5-DICARBONYL COMPOUNDS A GENERAL PREPARATION METHOD

In this report, a general method for the preparation of 1,5-dicarbonyl compounds and six membered ring annelation is described.This method involves the reaction of hemiacetal vinylogs 1 with enol ethers 2 or 3 in the presence of a Lewis acid.This reaction was successfully applied to the enol ethers of α and α,α'-hindered ketones such as 2,2,6-trimethyl cyclohexanone. α-Cyperone and 6-epi-α-cyperone were obtained using this process.

Production of 2,3,6-trimethylphenol

A process for the production of 2,3,6-trimethylphenol in which diethyl ketone is reacted in the presence of a basic reagent with crotonaldehyde or methyl vinyl ketone (or a compound which in the presence of a basic reagent is converted into crotonaldehyde or methyl vinyl ketone) and the 2,5,6-trimethyl-2-cyclohexen-1-one or 2,3,6-trimethyl-2-cyclohexen-1-one formed is dehydrogenated.