41632-11-5

Upstream product

• 149-57-5 2-Ethylhexanoic acid 
• 760-67-8 2-ethylhexanoic acid chloride 
• 816-19-3 methyl 2-ethylhexanoate 

Downstream Products

• 1203674-30-9 C₂₂H₃₀N₂O 

Relevant academic research and scientific papers

FLOW CHEMISTRY SYNTHESIS OF ISOCYANATES

The disclosure provides, inter alia, safe and environmentally-friendly methods, such as flow chemistry, to synthesize isocyanates, such as methylene diphenyl diisocyanate, toluene diisocyanate, hexamethylene diisocyanate, isophorone diisocyanate, and tetramethylxylene diisocyanate.

Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives

The inhibition of the β-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) and Candida albicans (Nce103) with a series of 25 branched aliphatic and aromatic carboxylates has been investigated. Human isoforms hCA I and II were also included in the study for comparison. Aliphatic carboxylates were generally millimolar hCA I and II inhibitors and low micromolar/submicromolar β-CA inhibitors. Aromatic carboxylates were micromolar inhibitors of the four enzymes but some of them showed low nanomolar activity against the fungal pathogenic enzymes. 4-Hydroxy- and 4-methoxy-benzoate inhibited Can2 with KIs of 9.5-9.9 nM. The methyl esters, hydroxamates, hydrazides and carboxamides of some of these derivatives were also effective inhibitors of the α- and β-CAs investigated here.

Physicochemical properties of 2-ethylhexanoic acid N′,N′- dialkylhydrazides

The following characteristics of 2-ethylhexanoic acid N′,N′- dialkyl(C4-C8)hydrazides relevant to their potential application as Cu(II) extractants were studied: solubility, acid-base properties, resistance to hydrolysis, loss with the aqueous phase, and distribution ratio in relation to the composition of the medium and length of alkyl chains. Nauka/Interperiodica 2006.