4166-67-0

Basic information

• Product Name: N-ETHYLMALEAMIC ACID
• Synonyms: N-ETHYLMALEAMIC ACID;Maleic acid monoethylamide;4-(ethylamino)-4-oxoisocrotonic acid;N-ETHYLMALEAMIC ACID, TECH. 85%;(2Z)-4-(Ethylamino)-4-oxo-2-butenoic acid;(Z)-4-Ethylamino-4-oxo-2-butenoic acid;N-Ethylmaleamidic acid;3-(ethylcarbamoyl)prop-2-enoic acid
• CAS NO: 4166-67-0
• Molecular Formula: C6H9NO3
• Molecular Weight: 143.14
• EINECS: 224-021-1
• Product Categories: monomer
• Mol File: 4166-67-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 124-126°C
• Boiling Point: 375 °C at 760 mmHg
• Flash Point: 180.6 °C
• Appearance: white solid
• Density: 1.175 g/cm³
• Vapor Pressure: 1.18E-06mmHg at 25°C
• Refractive Index: 1.488
• BRN: 1210030
• CAS DataBase Reference: N-ETHYLMALEAMIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-ETHYLMALEAMIC ACID(4166-67-0)
• EPA Substance Registry System: N-ETHYLMALEAMIC ACID(4166-67-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: 1759
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 4166-67-0(Hazardous Substances Data)

Usage

General Description

N-Ethylmaleamic Acid is a chemical compound with the formula C6H9NO3. It is also recognized by other names such as Maleamic acid, N-ethyl-4-pyridinecarbonyl chloride, and 2,5-Furandione. This organic compound belongs to the family of maleamic acids, which are organic compounds with the general formula R-CO2H. The ethyl group attached at the N atom is typically inert for acid-base chemistry. The behaviour of these molecules is mainly determined by the carboxylic acid group, which makes these compounds weakly acidic. It's mostly used in various industrial applications, although it should be handled with care due to its potential for harm to human health and the environment.

InChI:InChI=1/C6H9NO3/c1-2-7-5(8)3-4-6(9)10/h3-4H,2H2,1H3,(H,7,8)(H,9,10)/b4-3-

Upstream product

• 108-31-6 maleic anhydride 
• 75-04-7 ethylamine 
• 128-53-0 N-Ethylmaleimide 
• 108-78-1 2,4,6-triamino-s-triazine 

Downstream Products

• 128-53-0 N-Ethylmaleimide 
• 133102-24-6 N⁴-ethyl-N²-benzyl-asparagine 
• 119074-43-0 (Z)-Ethyl methyl maleamate 
• 350030-47-6 2-(1-ethyl-2,5-dioxo-pyrrolidin-3-ylmercapto)-benzoic acid 

Relevant articles and documents

Synthesis, characterization and thermal behavior of tetrakis(melamine2+) bis(melamine+) pentakis(monohydrogenphosphate) tetrahydrate

A new organic-inorganic salt, tetrakis (2,4,6-Triamino-1,3,5-Triazin-1,3-diium) bis (2,4,6-Triamino-1,3,5-Triazin-1-ium) pentakis (monohydrogenphosphate) tetrahydrate, 4C3H8N6+2. 2C3H7N6+. 5HPO42-. 4H2O was synthesized through the reaction of melamine and phosphoric acid in an acidic medium HCl/H2O. It was then characterized by X-ray diffraction. The title compound crystallizes in monoclinic system with non-centrosymetric space group P 21 with lattice parameters a = 11.3008 ?, b = 20.9798 ?, c = 12.2679 ?, α = 90°, β = 117.236°, γ = 90°, Z = 2 and V = 2586.10 (?)3. The UV-vis absorption spectrum UV-vis showed that the crystal has a good optical transmittance in the entire visible region with a lower cut off wavelength of 290 nm. The vibrational frequencies of various functional groups present in the crystal were identified by FT-IR analysis. The chemical structure of the compound was also confirmed by 1H, 13C and 31P NMR spectroscopy. TGA-DTA analysis revealed that the materials have a good thermal stability without any melting.

Synthesis and antifungal activity of N-(alkyl/aryl)-2-(3-oxo-1,4- benzothiazin-2-yl)acetamide

A series of N-(alkyl/aryl)-2-(3-oxo-1,4-benzothiazin-2-yl)acetamide have been synthesized by condensation of substituted amines with maleic anhydride (MA) followed by cyclization with o-aminothiophenol (o-ATP). All the compounds have been screened for their antifungal activity against Tricophyton rubrum, Epidermophyton floccosum and Malassazia furfur. In the primary screening, some of the compounds exhibited appreciable activity. The structures of the synthesized compounds 7a-z have been established on the basis of elemental analysis and spectral data.