41721-00-0 Usage
General Description
Pyrrolidine, 1-[(2S)-2-pyrrolidinylcarbonyl]- (9CI) is a chemical compound with the molecular formula C8H14N2O. It is a pyrrolidine derivative, which is a five-membered heterocyclic organic compound containing a nitrogen atom. This particular compound is a carboxylic acid amide, and it has a chiral center, meaning it exists in two enantiomeric forms. Pyrrolidine derivatives have various pharmaceutical and industrial applications, including as intermediates in the synthesis of pharmaceuticals and agrochemicals. They also have potential therapeutic properties in areas such as neurology, oncology, and infectious diseases. Further research and development into the properties and applications of this compound are ongoing.
Check Digit Verification of cas no
The CAS Registry Mumber 41721-00-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,7,2 and 1 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41721-00:
(7*4)+(6*1)+(5*7)+(4*2)+(3*1)+(2*0)+(1*0)=80
80 % 10 = 0
So 41721-00-0 is a valid CAS Registry Number.
41721-00-0Relevant articles and documents
Synthesis of chiral diamines using novel 2-trichloromethyloxazolidin-4-one precursors derived from 5-oxo-proline and proline
Amedjkouh, Mohamed,Ahlberg, Per
, p. 2229 - 2234 (2007/10/03)
Efficient syntheses of chiral vicinal diamines derived from (S)-oxo-proline and (S)-proline are described. The novel diastereomerically pure precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo-[3.3.0]-octan-4,8-dione 3 and its enantiomer are readily available by reaction of the inexpensive enantiomers of 5-oxo-proline with chloral. Compound 3 reacts with primary and secondary amines to afford the 5-oxo-prolylamides 4 in quantitative yield. In contrast, the (S)-proline-derived precursor (2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octan-4-one 6 gave (S)-N-formylprolylamides 9 and/or (S)-prolylamides 8 depending on the reaction conditions. Upon reduction with LiAlH4, amides 4 and 9 afforded the proline-derived (S)-2-(alkylaminomethyl)pyrrolidines 1 and (S)-N-methyl-2-(alkylaminomethyl)-pyrrolidines 5 in 70-90% yields.
