41723-91-5

Upstream product

• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 15590-23-5 sodium methylsulfinylmethanide 

Downstream Products

• 551-11-1 dinoprost 
• 1240483-23-1 (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoic acid 
• 1289580-06-8 (Z)-7-((1R,2R,3R,5S)-5-(tert-butyldimethylsilyloxy)-2-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)-3-hydroxycyclopentyl)hept-5-enoic acid 
• 1240483-17-3 (Z)-7-((1R,2R,3R,5S)-3-((tert-butyldimethylsilyl)oxy)-2-((S,E)-3-((tert-butyldimethylsilyl)oxy)-5-phenylpent-1-en-1-yl)-5-hydroxycyclopentyl)hept-5-enoic acid 
• 1289580-02-4 (Z)-7-((1R,2R,3R,5S)-5-(tert-butyldimethylsilyloxy)-2-((S,E)-3-(tert-butyldimethylsilyloxy)-5-phenylpent-1-enyl)-3-hydroxycyclopentyl)hept-5-enoic acid 
• 1240483-19-5 (Z)-7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((S,E)-3-(tert-butyldimethylsilyloxy)-5-phenylpent-1-enyl)-5-hydroxycyclopentyl)-N-ethylhept-5-enamide 
• 155206-00-1 bimatoprost 
• 130209-82-4 latanoprost 
• 474944-22-4 (Z)-isopropyl 7-((1R,2R,3R,5S)-3-(tert-butyldimethylsilyloxy)-2-((R)-3-(tert-butyldimethylsilyloxy)-5-phenylpentyl)-5-hydroxycyclopentyl)hept-5-enoate 
• 134828-96-9 (Z)-7-[(1R,2R,3R,5S)-2-[(E)-(S)-6-[3-(4-Azido-2,3,5,6-tetrafluoro-benzyloxymethyl)-5-iodo-phenoxy]-3-(tert-butyl-dimethyl-silanyloxy)-hex-1-enyl]-3,5-bis-(tert-butyl-dimethyl-silanyloxy)-cyclopentyl]-hept-5-enoic acid methyl ester 
• 145293-39-6 (Z)-7-((1R,2R,3R,5S)-2-{(E)-(S)-6-[3-(4-Azido-2,3,5,6-tetrafluoro-benzyloxymethyl)-5-iodo-phenoxy]-3-hydroxy-hex-1-enyl}-3,5-dihydroxy-cyclopentyl)-hept-5-enoic acid methyl ester 
• 91874-07-6 ((Z)-2,16-Dioxo-hexadec-6-enyl)-triphenyl-phosphonium; chloride 
• 91874-04-3 ((Z)-2,13-Dioxo-tridec-6-enyl)-triphenyl-phosphonium; chloride 
• 91874-03-2 (Z)-15-[1,3]Dioxolan-2-yl-1-(triphenyl-λ⁵-phosphanylidene)-pentadec-6-en-2-one 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF F-SERIES PROSTAGLANDINS

A process for the synthesis and purification of F-series prostaglandin compounds and synthetic intermediates used to prepare them. The synthetic intermediates are solid and may be purified by precipitation and therefore may form the representative F-series prostaglandin compounds such as latanoprost, bimatoprost, fluprostenol, cloprostenol, and substituted analogs therefrom in highly pure forms.

Didemnilactones A and B and Neodidemnilactone, Three New Fatty Acid Metabolites Isolated from the Tunicate Didemnum moseleyi (Herdman)

Three new fatty acid metabolites didemnilactones A (1) and B (2) and neodidemnilactone (3) were isolated from the tunicate Didemnum moseleyi (Herdman).Their structures including absolute stereochemistry were established on the basis of spectral studies an

PROSTANOIDS. LIX. ENANTIODIVERGENT SYNTHESIS OF (+)- AND (-)-9,11-DIDESOXY-9,11-ETHANO ANALOGS OF PROSTAGLANDIN ENDOPEROXIDE AND THEIR C15-DIASTEREOMERS

Schemes are described for the transformation of (-)-(1S,2S,3S,6R,7R,9R)-10,12-dioxatetracyclo3,6.02,7>tridecan-8-one obtained by the hydrogenation of the endo adduct synthesized in the Diels-Alder reaction from levoglucosenon

Prostaglandins. 2. Synthesis of Prostaglandin F2α in Optically Active Form from Chiral Precursors

A synthetic route to optically active prostaglandins is described which use chiral starting materials.Acylation of the bis(magnesiobromide) salt of methyl hemimalonate with (S)-(-)-2-acetoxysuccinyl chloride led to unstable dimethyl (S)-4-acetoxy-3,6-diox

A NOVEL APPROACH TO THE SYNTHESIS OF 8-METHYL PROSTAGLANDINS

A synthesis of 8-methyl prostaglandins is described.Starting from a chiral cyclic keto lactone, C1-homologation with dimethyl oxosulfonium methylide is used as key reaction in the sequence. 8-Methyl prostaglandin C2 and its methyl es