41727-18-8Relevant articles and documents
Enantioselective Ni-Catalyzed Electrochemical Synthesis of Biaryl Atropisomers
Chen, Song,Chen, Yue-Gang,Gao, Pei-Sen,Liu, Dong,Ma, Hong-Xing,Mei, Tian-Sheng,Qiu, Hui,Shuai, Bin,Wang, Yun-Zhao
supporting information, p. 9872 - 9878 (2020/06/27)
A scalable enantioselective nickel-catalyzed electrochemical reductive homocoupling of aryl bromides has been developed, affording enantioenriched axially chiral biaryls in good yield under mild conditions using electricity as a reductant in an undivided cell. Common metal reductants such as Mn or Zn powder resulted in significantly lower yields in the absence of electric current under otherwise identical conditions, underscoring the enhanced reactivity provided by the combination of transition metal catalysis and electrochemistry.
Ligand Tuning in Pyridine-Alkoxide Ligated Cp?IrIII Oxidation Catalysts
Sackville, Emma V.,Kociok-K?hn, Gabriele,Hintermair, Ulrich
supporting information, p. 3578 - 3588 (2017/10/03)
Six novel derivatives of pyridine-alkoxide ligated Cp?IrIII complexes, potent precursors for homogeneous water and C-H oxidation catalysts, have been synthesized, characterized, and analyzed spectroscopically and kinetically for ligand effects. Variation of alkoxide and pyridine substituents was found to affect their solution speciation, activation behavior, and oxidation kinetics. Application of these precursors to catalytic C-H oxidation of ethyl benzenesulfonate with aqueous sodium periodate showed that the ligand substitution pattern, solution pH, and solvent all have pronounced influences on initial rates and final conversion values. Correlation with O2 evolution profiles during C-H oxidation catalysis showed these competing reactions to occur sequentially, and demonstrates how it is possible to tune the activity and selectivity of the active species through the NO ligand structure.
Manganese-Catalyzed Direct Nucleophilic C(sp2)-H Addition to Aldehydes and Nitriles
Zhou, Bingwei,Hu, Yuanyuan,Wang, Congyang
supporting information, p. 13659 - 13663 (2015/11/16)
Herein, a manganese-catalyzed nucleophilic addition of inert C(sp2)-H bonds to aldehydes and nitriles is disclosed by virtue of a dual activation strategy. The reactions feature mild reaction conditions, excellent regio- and stereoselectivity, and a wide substrate scope, which includes both aromatic and olefinic C-H bonds, as well as a large variety of aldehydes and nitriles. Moreover, mechanistic studies shed light on possible catalytic cycles.
Aggregative activation in heterocyclic chemistry. Part 5. Lithiation of pyridine and quinoline with the complex base BuLi·Me2N(CH2)2OLi (BuLi·LiDMAE)
Gros, Philippe,Fort, Yves,Caubere, Paul
, p. 3597 - 3600 (2007/10/03)
It is shown that the complex base BuLi·LiDMAE reacts with pyridine to give metallated species which, after trapping by electrophiles, lead to 2-substituted pyridines in good to excellent yields. The same reactions have been less successfully performed with quinoline.
Lewis Acid Complexed Heteroatom Carbanions; Synthesis of some α-Pyridyl Alcohols
Kessar, Satinder V.,Singh, Paramjit,Singh, Kamal Nain,Dutt, Mahesh
, p. 570 - 571 (2007/10/02)
Metallation of BF3-pyridine complex with lithium tetramethylpiperidide (LTMP) in ether at -78 deg C, followed by reaction with carbonyl compounds, affords α-pyridyl alcohols in good yields.
