417722-21-5

Basic information

• Product Name: 5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE
• Synonyms: 5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE;5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-Pyridinamine
• CAS NO: 417722-21-5
• Molecular Formula: C₁₆H₁₅N₃O₃
• Molecular Weight: 297.3086
• Mol File: 417722-21-5.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE(417722-21-5)
• EPA Substance Registry System: 5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE(417722-21-5)

Safety Data

• Hazardous Substances Data: 417722-21-5(Hazardous Substances Data)

Usage

General Description

5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE is a chemical compound with the molecular formula C17H17N3O3. It is a complex organic compound that consists of a pyridine ring combined with an amine group and a quinolin-4-yl subunit, which contains two methoxy groups at the 6th and 7th positions. 5-[(6,7-DIMETHOXYQUINOLIN-4-YL)OXY]PYRIDIN-2-AMINE is commonly used in pharmaceutical research and drug development due to its potential therapeutic properties. It has been studied for its potential applications in various medical conditions, including cancer, inflammation, and neurological disorders. Additionally, its unique molecular structure makes it a promising candidate for further research and potential drug development.

Upstream product

• 55717-46-9 6-aminopyridin-3-ol 
• 35654-56-9 6,7-dimethoxy-4-chloroquinoline 
• 109-00-2 3-HYDROXYPYRIDINE 
• 52092-47-4 5-chloro-2-nitropyridine 
• 6315-89-5 3,4-dimethoxyaniline 
• 26717-39-5 [[(3,4-Dimethoxyphenyl)amino]methylene]malonic acid,diethyl ester 
• 13436-14-1 ethyl 4-hydroxy-6,7-dimethoxyquinoline-3-carboxylate 
• 856965-37-2 2-amino-5-hydroxypyridine hydrochloride 
• 41288-96-4 6-chloropyridine-3-ol 
• 1355031-22-9 4-((6-bromopyridin-3-yl)oxy)-6,7-dimethoxyquinoline 
• 55717-45-8 6-bromo-pyridin-3-ol 
• 779345-37-8 5-fluoro-2-nitro-pyridine 
• 13425-93-9 6,7-dimethoxyquinoline-4-ol 
• 1000850-78-1 6,7-dimethoxy-4-((6-nitropyridin-3-yl)oxy)quinoline 

Relevant articles and documents

Structure activity relationships of quinoline-containing c-Met inhibitors

A series of quinoline-containing c-Met inhibitors were prepared and studied. Chemistry was developed to introduce a pyridyl moiety onto the 2-aryl ring present in a lead molecule which mitigated the potential for quinone formation relative to the original

Novel quinoline derivative inhibitor

The invention provides a novel quinoline derivative inhibitor, which has a structure represented by the following general formula (I). According to the invention, the compound provided by the invention can selectively inhibit tyrosine kinase TAM family/an

TAM family kinase and/or CSF1R kinase inhibitor and application thereof

The invention provides a novel inhibitor compound shown in a general formula (I). The compound has good kinase inhibition activity and can be used for preventing and/or treating diseases mediated by abnormal expression of TAM family kinase and/or a ligand thereof. The compound can target CSF1R kinase and can be used for preventing and/or treating diseases mediated by abnormal expression of a TAM family kinase receptor and/or a CSF1R kinase receptor and/or ligands thereof.