41796-89-8Relevant articles and documents
STAGES OF THE CONDENSATION OF 1,4-BUTANEDIOL IN THE MARKOVNIKOV - GUERBET REACTION
Lyubomilov, V. I.,Slesareva, L. A.,Pshenitsyna, V. P.,Slonim, I. Ya.,Bulai, A. Kh.
, p. 1871 - 1874 (2007/10/02)
The condensation of 1,4-butanediol in the presence of its sodium alcoholate and Ni/Cr2O3 leads to the formation of 4-hydroxybutanal and, from the latter, 3-formyl-1,4,7-heptanetriol.The latter exists in equilibrium with 1,7-dihydroxy-3-hydroxymethyl-4-heptanone and 2-hydroxy-2-(1-hydroxymethyl-3-hydroxypropyl)tetrahydrofuran.Dehydration of the latter with the formation of an endocyclic double bond and subsequent isomerization and reduction processes lead to the production of 2-(1-hydroxymethyl-3-hydroxypropyl)tetrahydrofuran.
